Sökning: "PGES"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet PGES.

  1. 1. Molecular genetic studies of oxidative stress related genes

    Författare :Louise Lyrenäs; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Gene regulation; oxidative stress; genetic variation; catalase; MGST1; PGES;

    Sammanfattning : This work has focused on the basal characterisation of transcriptional regulation, including genetic variants, in oxidative stress related genes and the possible impact of such variation in cardiovascular disease. The genes under study were catalase and MGST1/PGES where the two former protect from hydrogen peroxide and lipid hydroperoxides respectively and the latter is important in e. LÄS MER

  3. 2. Expression of prostaglandin E synthase-1 in periodontitis : in vivo and in vitro studies

    Författare :Anna Kats; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Periodontitis is a chronic inflammatory disease characterized by destruction of the supporting structures of the teeth, including gingival tissues and alveolar bone. In advanced cases of periodontitis the ultimate clinical outcome is tooth loss. LÄS MER

  4. 3. Characterization of human glutathione-dependent microsomal prostaglandin E synthase-1

    Författare :Staffan Thorén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostaglandins (PGs) are lipid mediators, which act as local hormones. PGs are formed in most calls and are synthesized de novo from membrane-released arachidonic acid (AA) upon cell activation. LÄS MER

  5. 4. Studies of prostaglandin E2 formationin human monocytes

    Författare :Sofia Karlsson; Jonny Wijkander; Christina Gustafson-Svärd; Karlstads universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostaglandin E2; arachidonic acid; phospholipase A2; cyclooxygenase; prostaglandin E synthase; human monocytes; Medical cell biology; Medicinsk cellbiologi; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : Prostaglandin (PG) E2 is an eicosanoid derived from the polyunsaturated twenty carbon fatty acid arachidonic acid (AA). PGE2 has physiological as well as pathophysiological functions and is known to be a key mediator of inflammatory responses. LÄS MER

  7. 5. Traffic-related pollutants in urban snow : Concentrations, size fractionation, and release with snowmelt

    Författare :Arya Vijayan; Maria Viklander; Helene Österlund; Göran Blomqvist; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Urban snow; Traffic pollution; Suspended solids; Metals; PAHs; Tire and Road wear Particles T RWPs ; Microplastics MPs ; Size fractionation; VA-teknik; Urban Water Engineering; Centrumbildning - Centrum för dagvattenhantering DRIZZLE ; Centre - Centre for Stormwater Management DRIZZLE ;

    Sammanfattning : In urban areas with seasonal snow, traffic-related pollutants such as solid particles, metals, chloride, organic pollutants, and microplastics (MPs) can be temporarily stored in snowbanks along roads and streets. When the snow melts, it releases the accumulated pollutants and the resulting snowmelt with diverse pollutants may partly infiltrate into the ground, or enter storm sewers and eventually be discharged into, and impact on, the receiving waters. LÄS MER