Sökning: "KI serotonin"

Visar resultat 21 - 25 av 143 avhandlingar innehållade orden KI serotonin.

  1. 21. Interaction between the nervous and immune systems in allergic contact dermatitis : a clinical and experimental study with emphasis on the role of VIP and serotonin

    Författare :Lena Bondesson Lundeberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :patch test; nickel sulphate; serotonin antagonists; VIP receptors; immunohistochemistry; ELISA; RIA; HPLC;

    Sammanfattning : The interaction between the nervous and immune systems was investigated in allergic contact dermatitis (ACD) with emphasis on the role of vasoactive intestinal peptide (VIP) and serotonin (S-HT). Dual dose-dependent effects of VIP on the migration of mononuclear and polymorphonuclear leukocytes were found. LÄS MER

  3. 22. A PET study on dopamine and serotonin receptor binding in the primate brain : challenges with antipsychotic drugs and amphetamine

    Författare :Yuan-Hwa Chou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The brain imaging technique positron emission tomography (PET) has been applied to study dopamine and serotonin neurotransmission. In schizophrenia research, an important observation is that patients with schizophrenia, when compared with controls, have higher amphetamine induced dopamine release in the striatum. LÄS MER

  4. 23. Interactions between the opioid and serotonin systems in chronic pain : quantitative live cell study by fluorescence cross-correlation spectroscopy (FCCS)

    Författare :Vlad Radoi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic pain is a major health issue worldwide. It enacts considerable suffering on the affected individuals and significantly increases the societal burden, as it is the most common reason why individuals seek sick leave and ask for medical help. LÄS MER

  5. 24. In vivo and in vitro studies of the serotonin 1B receptor in relation to major depressive disorder and treatment with ketamine

    Författare :Emma R Veldman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite the large implications of Major Depressive Disorder (MDD) on disease burden worldwide, current treatment options are suboptimal and a third of patients suffering from this disease do not respond to treatment. Therefore, an unmet need exists for the development of new treatment options and methods to aid appropriate treatment selection in individual patients. LÄS MER

  7. 25. Development of radioligands for the serotonergic neurotransmission system for use in positron emission tomography

    Författare :Johan Sandell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PET; Radioligand; Brain; 5-HT1A receptor; serotonin transporter;

    Sammanfattning : The serotonergic system is implicated in several neuropsychiatric disorders, such as depression, anxiety and schizophrenia. Several hypotheses on the pathophysiology of these disorders are based on the pharmacology of serotonergic drugs. Selective serotonin reuptake inhibitors (SSRIs) are widely used for the treatment of depression and anxiety. LÄS MER