Sökning: "KI serotonin"

Visar resultat 16 - 20 av 143 avhandlingar innehållade orden KI serotonin.

  1. 16. The longitudinal biology of depression : PET studies of the dopamine and serotonin systems

    Författare :Jonas Svensson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The involvement of monoamine neurotransmission in the pathophysiology of depression was established already in the 1960s. However despite an abundance of research, the exact role of the serotonin (5-HT) and dopamine systems in depression have remained elusive. LÄS MER

  3. 17. Significance of serotonin for pain, allodynia, and hyperalgesia in the human masseter muscle

    Författare :Malin Ernberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Anxiety; Double-Blind Method; 5-Hydroxytryptamine; Fibromyalgia; Hyperalgesia; Masseter muscle; Microdialysis; Pain threshold; Visual Analogue Pain Scale;

    Sammanfattning : The main aim of this thesis was to investigate the hypothesis that serotonin (5-HT) is involved in the pathophysiology of human chronic muscle pain. The thesis comprises a clinical and a human experimental part. LÄS MER

  4. 18. Distribution of serotonin receptors and transporters in the human brain : implications for psychosis

    Författare :Katarina Varnäs; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :5-HT receptors; autoradiography; in situ hybridization histochemistry; psychotic disorders;

    Sammanfattning : The serotonin (5-HT) system is thought to be involved in different psychiatric disorders, including depression and anxiety disorders, and is a major target for the pharmacological treatment of these conditions. The involvement of the 5-HT system in psychosis has been suggested, as 5-HT receptor agonism is a common mechanism of different classes of hallucinogenic drugs and several antipsychotics are 5-HT receptor antagonists. LÄS MER

  5. 19. Assessment of dopamine and serotonin release in the non-human primate brain using PET

    Författare :Sjoerd J. Finnema; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The molecular imaging technique positron emission tomography (PET) allows for non-invasive examination of biochemical markers in the living brain. For over three decades PET studies have provided important insight into the relationship of monoaminergic neurotransmitter systems to brain functioning and psychiatric disorders. LÄS MER

  7. 20. In vitro studies on intestinal epithelial cell proliferation : effects of cytokines, Helicobacter pylori, serotonin and neuroendocrine peptides

    Författare :Kristina Zachrisson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ammonia; Apoptosis; cell culture; cytokines; DNA synthesis; FHs-74 cells; Helicobacter pylori; IEC-6 cells; mitosis; neuroendocrine peptides; organ culture; serotonin;

    Sammanfattning : Previous studies suggest that bacteria and bacterial metabolites, proinflammatory cytokines, neuroendocrine peptides and amines may participate in the regulation of the gastrointestinal-epithelial cell kinetics. The complexity of interactions that take place in vivo makes it difficult to define the primary actions of these and other agents on gastrointestinal cell proliferation. LÄS MER