Sökning: "Genetic predisposition"

Visar resultat 31 - 35 av 160 avhandlingar innehållade orden Genetic predisposition.

  1. 31. Clinical and genetic aspects on cluster headache

    Författare :Christina Sjöstrand; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cluster headache; natural history; familial CH; atypical CH; genetics; association; linkage; gene expression;

    Sammanfattning : Cluster headache (CH), a primary neurovascular headache syndrome, is characterized by recurrent, unilateral, short-lasting attacks of excruciating pain in the temporal region. The pain is considered one of the most severe pain conditions known to humans. LÄS MER

  3. 32. The genetic contribution to stroke in northern Sweden

    Författare :Tomas Janunger; Dan Holmberg; Holger Luthman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Northern Sweden; stroke; genetics; genome wide scan; association; 5q13; 9q31-33; Medical genetics; Medicinsk genetik; medicinsk genetik; Medical Genetics;

    Sammanfattning : Stroke is a common multi factorial cerebrovascular disorder with a large impact on global health. It is a disorder primarily associated with old age but environmental factors, lifestyle choices and medical history are all important for the risk of developing the disorder. LÄS MER

  4. 33. Understanding the genetic architecture of fatty liver disease

    Författare :Jamialahmadi Oveis; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-alcoholic fatty liver disease; Polygenic risk score; Genomewide association studies; Mendelian Randomization;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, ranging from simple steatosis to more severe conditions, namely non-alcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). NAFLD has a strong genetic component, and its heritability depends on environmental factors and ethnicity. LÄS MER

  5. 34. Genetic predispositions to rheumatoid arthritis in Malaysian population

    Författare :Chun Lai Too; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Genetic predisposition is a significant and fundamental determinant of susceptibility to rheumatoid arthritis (RA), a complex autoimmune disease with a painful and disabling condition. The vast majority of genetic studies in RA have been centered on populations of European descent with very few studies on East Asian populations. LÄS MER

  7. 35. Biological ages : correlations, genetic determinants, and health outcomes

    Författare :Xia Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Population aging is a global trend and requires better evidence-based guidance. This thesis studied population aging from a molecular epidemiological angle. LÄS MER