Sökning: "Fractionated irradiation"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden Fractionated irradiation.

  1. 6. Astatine-211 radioimmunotherapy of ovarian cancer. Therapeutic efficacy, myelotoxicity, andradiation dosimetry in an animal model

    Författare :Jörgen Elgqvist; Göteborgs universitet; []
    Nyckelord :astatine; alpha-particles; monoclonal antibodies; radioimmunotherapy; ; ovarian cancer; myelotoxicity; therapeutic efficacy; radiation dosimetry; fractionation;

    Sammanfattning : Alpha-particle emitting radionuclides have recently obtained an increased attention whenconsidering new strategies for treating disseminated cancer. Astatine (211At), that emits alphaparticleswith a mean path length of 62 μm, a mean linear energy transfer (LET) of 111keV/Mum, and a half-life of 7. LÄS MER

  3. 7. Microarray gene expression in immunological conditions

    Författare :Abdulkareem Musa Heevy Al-Chaqmaqchi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The use of microarray techniques for gene expression analysis provides a global view of the transcriptional activity in a biological sample. In this thesis two conditions accompanied by disturbance in the immune system are addressed following the changes in gene expression. LÄS MER

  4. 8. Visual outcome, ocular findings, and visual processing skills after allogeneic stem cell transplantation in children

    Författare :Alba Lucia Törnquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Stem cell transplantation (SCT) offers a chance of cure in children with leukaemia and other life-threatening haematological, immunological, and metabolic diseases that do not respond to conventional treatment. Pre and post SCT, these children receive irradiation, and/or chemotherapy and immunosuppressive agents which like the primary disease may adversely affect the eye, the central nervous system as well as the posterior visual pathways and potentially threaten vision. LÄS MER

  5. 9. Conditioning associated effects on oral mucosa and salivary function in allogeneic stem cell recipients

    Författare :Karin Garming Legert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allogeneic hematopoietic stem cell transplantation (HSCT) is an effective treatment for patients with a range of disorders of the immunohematopoietic system. In HSCT recipients, acute complications in the oral cavity are common. LÄS MER

  7. 10. Strategies to improve cancer radioimmunotargeting

    Författare :Anders Ullén; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; : cancer; monoclonal antibody; antiidiotypic antibody; radioimmunotargeting; placental alkaline phosphatase; cytokeratin; BIAcore.;

    Sammanfattning : Radioimmunotherapy (RIT) and radioimmunolocalisation (RIL) are developing and promising technologies to diagnose and treat tumours by use of radiolabelled antibodies targeting tumour specific antigens. The major reason why RIL and RIT not are efficient enough, is the comparatively low accumulation of radiolabelled antibodies in the tumours. LÄS MER