Sökning: "Estrogen receptor beta"

Visar resultat 16 - 20 av 63 avhandlingar innehållade orden Estrogen receptor beta.

  1. 16. Role and mechanism of estrogen receptor beta in the ovary and colon

    Författare :Madeleine Birgersson; Cecilia Williams; Amena Archer; Claudia Kutter; Eduardo Villablanca; David Moore; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinsk teknologi; Medical Technology;

    Sammanfattning : Estrogen regulates a variety of important physiological functions in both males and females, where the regulation of female reproduction and the development of sexual organs are typical examples. The effects of estrogen are predominantly exerted via signaling through the two nuclear receptors estrogen receptor α (ERα) and β (ERβ), or the membrane G protein-coupled estrogen receptor 1 (GPER1). LÄS MER

  3. 17. Antiproliferative action of estrogen receptor beta and Hes-1 in breast cancer

    Författare :Johan Hartman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Breast cancer is the most common malignancy among Swedish women. Although the mechanism behind the tumorigenesis remains unclear, estrogen receptor a (ERa) plays an important role in the progression of breast cancer and is regarded as a target for endocrine therapy. LÄS MER

  4. 18. Estrogen receptor beta transcriptional regulation: A potential mechanism for colon cancer prevention

    Författare :Rajitha Indukuri; Cecilia Williams; Jason Carroll; KTH; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical Technology; Medicinsk teknologi;

    Sammanfattning : Colorectal cancer (CRC) is the third leading cause of death from cancer in both men andwomen in the Western world. Improved screening efforts, surveillance, and treatment havereduced CRC mortality in older patients. However, the incidence is increasing in young adults,even in the absence of CRC family history. LÄS MER

  5. 19. Molecular characterization of estrogen receptor beta variants : cancer cell proliferation and invasion

    Författare :Li Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogen plays crucial roles in the pathogenesis of breast cancer. Most of the known effects of estrogen signaling are mediated by estrogen receptors (ERs), ERα and ERβ. ERα is explored for breast cancer molecular classification and is a target of endocrine therapy. LÄS MER

  7. 20. Role and mechanism of estrogen receptor beta in the physiology of the ovary and colon

    Författare :Madeleine Birgersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogen regulates a variety of important physiological functions in both males and females, where the regulation of female reproduction and the development of sexual organs are typical examples. The effects of estrogen are predominantly exerted via signaling through the two nuclear receptors estrogen receptor α (ERα) and β (ERβ), or the membrane G protein-coupled estrogen receptor 1 (GPER1). LÄS MER