Sökning: "Endocrine disrupting chemicals EDCs"

Visar resultat 11 - 15 av 18 avhandlingar innehållade orden Endocrine disrupting chemicals EDCs.

1. 11. Fewer kids not always by choice : the link between endocrine-disrupting chemicals and female reproductive health

   Författare :Richelle Duque Björvang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Fertility rates are declining from five children per woman in the 1950s to less than three children per woman in 2019. While this is partly due to women choosing to have fewer kids, there are growing evidence that endocrine-disrupting chemicals (EDCs) in the environment may play a role in this phenomenon. LÄS MER

3. 12. Effects of endocrine disruptors on adreno-cortical and Leydig cell steroidogenesis

   Författare :Vichit Supornsilchai; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Endocrine disrupting chemicals EDCs ; steroidogenesis; Leydig cells; adrenocortical cells; steroidogenic acute regulatory protein StAR ; steroidogenic enzymes;

   Sammanfattning : A common sequential pathway for steroidogenesis, designed to produce steroid hormones, is expressed in the adrenal cortex, testes and ovaries. In this process, cholesterol is converted to all known steroids by specific enzymes in a tissue-specific manner. LÄS MER

4. 13. Diverse effects of endocrine-disruptive chemicals on Leydig and adrenocortical cell steroidogenesis in rodents and humans

   Författare :Iuliia Savchuk; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : We are living in a man-made world and often exposed to different chemicals known as endocrine disrupting chemicals (EDCs) that negatively influence our hormonal system. These compounds have the potential to interrupt a normal steroidogenesis and result in harmful effects on the reproductive health of humans and among other organisms. LÄS MER

5. 14. Zebrafish as a model to study the neuroendocrine system and toxicity of endocrine disruptors

   Författare :Gayathri Chandrasekar; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Zebrafish is a popular vertebrate model system to study development and perform genetic analysis. It offers numerous advantages such as small size, short generation time, high fecundity, rapid and ex utero development of embryos and optically transparent embryos. LÄS MER

7. 15. Environmental Contaminants and Obesity

   Författare :Monika Rönn; P. Monica Lind; Lars Lind; Jan Örberg; Merete Eggesbø; Uppsala universitet; []
   Nyckelord :Fischer 344; rat; obesity; adipose tissue; persistent organic pollutants; POPs; bisphenol A; BPA; pesticides; dioxin; PCB; DDT; apo A-I; adiponectin; leptin; ghrelin;

   Sammanfattning : Obesity is a worldwide problem affecting both children and adults. Genetic, physiological, environmental, psychological, social and economic factors interact in varying degrees, influencing body weight and fat distribution and the progress of obesity. LÄS MER