Sökning: "steroidogenic acute regulatory protein StAR"

Hittade 4 avhandlingar innehållade orden steroidogenic acute regulatory protein StAR.

  1. 1. Effects of endocrine disruptors on adreno-cortical and Leydig cell steroidogenesis

    Författare :Vichit Supornsilchai; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Endocrine disrupting chemicals EDCs ; steroidogenesis; Leydig cells; adrenocortical cells; steroidogenic acute regulatory protein StAR ; steroidogenic enzymes;

    Sammanfattning : A common sequential pathway for steroidogenesis, designed to produce steroid hormones, is expressed in the adrenal cortex, testes and ovaries. In this process, cholesterol is converted to all known steroids by specific enzymes in a tissue-specific manner. LÄS MER

  3. 2. Autocrine and paracrine regulation of Leydig cell survival in the postnatal testis

    Författare :Eugenia Colón; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IGFs; steroidogenesis; Leydig cells; steroidogenic acute regulatory protein StAR ; insulin; IGFBP-3; IGFBP-2 and steroidogenic enzymes;

    Sammanfattning : The primary function of testicular Leydig cells is the production of androgens that promote sexual differentiation in the fetus, secondary sexual maturation at the. time of puberty, and spermatogenesis in the adult. LÄS MER

  4. 3. Hormonal and paracrine influences on Leydig cell steroidogenesis

    Författare :Nina Renlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Androgen production by Leydig cells is critical for development of the male reproductive organs and for maintaining normal body homeostasis and fertility later in life. Biosynthesis of testosterone is driven by secretion of the gonadotropin, luteinizing hormone (LH) from the pituitary. LÄS MER

  5. 4. The roles of the plasminogen activator and matrix metalloproteinase systems in ovulation and corpus luteum formation

    Författare :Ida Bodén; Umeå universitet; []
    Nyckelord :ovary; ovulation; corpus luteum; plasminogen; PA; MMP; mouse;

    Sammanfattning : Proteases of the plasminogen activator (PA) and the matrix metalloproteinase (MMP) enzyme systems are expressed in the ovulatory follicle and in the developing corpus luteum (CL). However, the functional role of these extracellular degrading protease systems in the ovulatory and CL development processes remains elusive. LÄS MER