Sökning: "Deep vein thrombosis"

Visar resultat 6 - 10 av 22 avhandlingar innehållade orden Deep vein thrombosis.

1. 6. Venous thromboembolism. Aspects on risk factors, diagnostic tools and treatment with thrombin inhibition

   Författare :Karin Wåhlander; Göteborgs universitet; []
   Nyckelord :deep vein thrombosis; pulmonary embolism; venous thromboembolism; Factor V Leiden; prothrombin gene G20210A; thrombin inhibition; ximelagatran; melagatran; PT; APTT; D-dimer.;

   Sammanfattning : Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), is a multifactorial disease. The aims of the present thesis were to investigate Factor V Leiden and prothrombin G20210A mutations as potential risk factors for VTE during and after major surgery, to compare different D-dimer assays and evaluate their usefulness in the diagnosis of DVT, to investigate clinical effects, safety and pharmacokinetic properties of an oral thrombin inhibitor (ximelagatran) when treating VTE and finally to investigate the usefulness of coagulation assays (APTT and PT) during treatment with thrombin inhibition. LÄS MER

3. 7. Arterial Thrombosis in Factor V Leiden or Activated Protein C Resistance. Clinical and Experimental Studies

   Författare :Ellis Sampram; Malmö Klinisk koagulationsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Activated protein c resistance; Factor V Leiden mutation; thrombophilia; hypercoagulable state; Factor V Leiden mice; arterial thrombosis; venous thromboembolism; peripheral vascular reconstructions; peripheral vascular reconstruction occlusion;

   Sammanfattning : Abstract The last two decades has seen an avalanche of studies establishing Activated protein C (APC) resistance due to Factor V Leiden mutation as the most prevalent genetic risk factor, yet known, for venous thromboembolism. This has been documented in 20-60% of patients with deep vein thrombosis (DVT). LÄS MER

4. 8. Primary deep vein thrombosis in an upper limb : a retrospective study with an emphasis on the pathogenesis and late sequelae

   Författare :Thomas Arnhjort; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Upper extremity deep vein thrombosis (UEDVT) is an uncommon disease with an incidence of 1–11% of all deep vein thrombosis. UEDVT can be classified into two groups, primary and secondary UEDVT. Primary UEDVT includes idiopathic and effort-related UEDVT. Secondary UEDVT is caused by central venous devices, trauma, and cancer. LÄS MER

5. 9. Haemostatic function in precocious myocardial infarction and vein graft occlusion after coronary artery bypass grafting

   Författare :Elisabeth Moor; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The present study examined the role of blood coagulation and fibrinolytic function in patients with coronary heart disease in two settings; in patients with precocious myocardial infarction in whom thrombosis is considered to constitute an important pathogenic mechanism and in unselected patients undergoing coronary artery bypass grafting (CABG) in whom early thrombotic occlusion of vein grafts is a considerable problem. Particular attention was paid to coagulation factor Vll and the tissue factor pathway inhibitor (TFPI) in the young post-infarction patients. LÄS MER

7. 10. Thromboembolism following orthopaedic surgery : outcome and diagnostic procedures after prophylaxis in lower limb injuries

   Författare :Lasse Lapidus; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Orthopaedic surgery; deep vein thrombosis DVT ; pulmonary embolism PE ; colour duplex sonography; phlebography; fracture surgery; Achilles tendon rupture.;

   Sammanfattning : Deep vein thrombosis (DVT) and pulmonary embolism (PE) frequently occur after major orthopaedic surgery. The clinical assessment of DVT and PE is unreliable and most cases are asymptomatic. However, even in asymptomatic DVTs, the risk for a PE is considerable. LÄS MER