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Visar resultat 6 - 8 av 8 avhandlingar som matchar ovanstående sökkriterier.

  1. 6. Dispersal of ticks and their microorganisms by African-Western Palaearctic migratory birds

    Författare :Tove Hoffman; Björn Olsen; Åke Lundkvist; Kenneth Nilsson; Johan Normark; Uppsala universitet; []
    Nyckelord :African-Western Palaearctic; migratory birds; Ixodidae; Hyalomma rufipes; Ixodes; Alkhurma hemorrhagic fever virus; Anaplasma phagocytophilum; Francisella; Midichloria; Rickettsia aeschlimannii; PCR; microfluidic qPCR; metagenomics; Biologi; Biology;

    Sammanfattning : In Europe, tick-borne diseases are the most widespread and common vector-borne diseases and their geographical distribution is increasing. The dispersal of ticks depends on the movements of their vertebrate hosts. Avian hosts are more likely to be involved in long-distance range expansion of ticks due to their migration pattern. LÄS MER

  3. 7. Cell and organoid models to develop new antivirals and diagnostic methods for emerging viruses

    Författare :Aleksandra Pettke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The ongoing global pandemic of severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) is only the latest reminder of the urgent need for new antiviral strategies and diagnostic tools to improve preparedness for emergence of new pathogenic RNA-viruses. A key obstacle for the development of antivirals and diagnostic tools has been the lack of good models to study RNA viruses. LÄS MER

  4. 8. Advancing antiviral strategies against emerging RNA viruses by phenotypic drug discovery

    Författare :Marianna Tampere; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pathogenic RNA viruses can emerge from unexpected sources at unexpected times and cause severe disease in humans, as exemplified by the ongoing coronavirus disease 19 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Ebola virus (EBOV), Crimean-Congo hemorrhagic fever virus (CCHFV) and Zika virus (ZIKV) outbreaks from the past decade. Despite the increasing impact of emerging viruses to health and economy worldwide, our preparedness to stand against these diseases is hampered by the lack of approved and effective antiviral therapies. LÄS MER