Sökning: "Crimean Congo hemorrhagic fever virus"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Crimean Congo hemorrhagic fever virus.

  1. 1. Virus-host interactions : entry and replication of Crimean-Congo hemorrhagic fever virus

    Författare :Cecilia Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Crimean-Congo hemorrhagic fever (CCHF) is a severe acute human disease with potential lethal outcome caused by a virus, Crimean-Congo hemorrhagic fever virus (CCHFV). Not much is known regarding how CCHFV infects cells, replicates and why it cause vascular dysfunction. LÄS MER

  2. 2. Pathogenesis of an emerging pathogen - Crimean-Congo Hemorrhagic Fever Virus

    Författare :Anne-Marie Connolly-Andersen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Epithelial cells represent the first barrier to viral infection and the site of viral entry and release is often intimately connected with viral spread and pathogenesis. The plasma membrane of epithelial cells is polarized into an apical and basolateral domain separated by tight junctions (TJs). LÄS MER

  3. 3. Crimean-congo hemorrhagic fever virus : Interferon-induced antiviral mechanisms and immune evasion strategies

    Författare :Ida Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The Bunyaviridae family is the largest virus family consisting of more than 350 viruses. Despite the increasing knowledge regarding the biology of members of this family, little is known about Crimean-Congo hemorrhagic fever virus (CCHFV), a virus classified within the Nairovirus genus and the causative agent of a severe hemorrhagic fever in humans with high mortality. LÄS MER

  4. 4. Crimean-Congo hemorrhagic fever virus : Interactions with host cell structures in viral replication

    Författare :Melinda Simon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : p>Crimean-Congo hemorrhagic fever virus (CCHFV) is a human pathogen, and was first associated with its corresponding disease during an outbreak in the mid 1940s. At that time, outbreaks were mainly restricted to the former Soviet Union, Africa and Asia, but lately disease incidents have markedly risen and CCHFV is now also endemic in several countries in the Middle East and Europe. LÄS MER

  5. 5. Application of Padlock Probe Based Nucleic Acid Analysis In Situ

    Författare :Sara Henriksson; Mats Nilsson; Ulf Landegren; Harvest Gu; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probe; rolling circle amplification; single cell gel electrophoresis assay; comet assay; Crimean Congo hemorrhagic fever virus; Molecular medicine; Molekylär medicin; Molekylär medicin; Molecular Medicine;

    Sammanfattning : The great variation displayed by nucleic acid molecules in human cells, and the continuous discovery of their impact on life, consequently require continuous refinements of molecular analysis techniques. Padlock probes and rolling circle amplification offer single nucleotide discrimination in situ, a high signal-to-noise ratio and localized detection within cells and tissues. LÄS MER