Sökning: "Age-specific effects"

Visar resultat 11 - 15 av 16 avhandlingar innehållade orden Age-specific effects.

  1. 11. Effect of growth and development on tissue vulnerability : a study on the perinatal rat kidney

    Författare :Eva Serlachius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :apoptosis; development; DNA synthesis; growth; kidney; ontogeny; PKC; proximal tubular cells; pyelonephritis; rat; sodium; sodium deficiency;

    Sammanfattning : The infant is more vulnerable than older children and adults to pathological processes, such as metabolic disturbances and kidney infection. We have speculated that the vulnerability of the infant kidney may be related to the fact that the kidney at this time is undergoing rapid growth and development. LÄS MER

  2. 12. Alcohol use among older adults: Population perspectives on prevalence, correlates, and consequences of drinking in Swedish 70-year-olds

    Författare :Felicia Ahlner; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; septuagenarian; aged; alcohol consumption; drinking behavior; risk consumption; cohort studies; associated factors; longitudinal studies; public health; epidemiology;

    Sammanfattning : Background: Alcohol consumption is a major contributor to global morbidity and mortality, as well as accidents and intentional injuries. Older adults may be particularly susceptible to these negative consequences due to age-related factors that increase vulnerability to the adverse effects of alcohol. LÄS MER

  3. 13. Estrogen signaling in stroke : genetic and experimental studies

    Författare :Magnus Strand; Tommy Olsson; Jan Hillert; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; intracerebral hemorrhage; ischemic stroke; genetics; ERα; OPG; 17β-estradiol; enriched environment; learning and memory; hippocampus; NGFI-A; Medicine; Medicin;

    Sammanfattning : Stroke is a common and multifactorial disease influenced by genetic and environmental risk factors. It is a highly heterogeneous entity consisting of two main types, ischemic (80%) and hemorrhagic (20%) stroke. The most common form of hemorrhagic stroke is intracerebral hemorrhage (ICH). LÄS MER

  4. 14. Survivorship in Hodgkin lymphoma : childbearing and treatment-related disease

    Författare :Caroline E Weibull; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer is often considered a disease with, historically, poor survival that affects middle-aged and elderly individuals. Hodgkin lymphoma (HL) is a lymphatic malignancy that affects both young and old individuals, with the age-specific incidence curve having its first peak at ages 20-30 years. LÄS MER

  5. 15. Familial risks for cancer with reference to lung cancer

    Författare :Xinjun Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Familial cancer; population-based; hereditary factors; familial risk; lung neoplasms.;

    Sammanfattning : Familial aggregation of cancer may be due either to environmental factors shared by family members, or to shared genes. Familial clustering has been an avenue to the understanding of the etiology of cancer and has been a basis for clinical decisions and counseling, as well as guiding the identification of cancer-related genes. LÄS MER