Sökning: "ribosome display"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden ribosome display.

  1. 1. Ribosome display for selection and evolution of affibody molecules

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Sebastian Grimm; KTH.; [2011]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; ribosome display; phage display; combinatorial protein engineering; library; murine IgG1; SATB1; Ras; Raf; TECHNOLOGY Bioengineering Genetic engineering including functional genomics; TEKNIKVETENSKAP Bioteknik Genteknik inkl. funktionsgenomik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : Affinity proteins are invaluable tools in biotechnological and medical applications. This thesis is about combinatorial protein engineering principles for the generation of novel affinity proteins to purify mouse immunoglobulin, detect a potential cancer marker protein or inhibit a cell proliferation pathway. LÄS MER

  2. 2. Rational and combinatorial genetic engineering approaches for improved recombinant protein production and purification

    Detta är en avhandling från Stockholm : Bioteknologi

    Författare :Nina Bandmann; KTH.; [2007]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Aqueous two-phase system; combinatorial library; expression vector; flow cytometry; fusion tag; partitioning; peptide library; phage display; recombinant proteins; ribosomal binding site; translation initiation; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Sammanfattning : The bacterium Escherichia coli (E. coli) is in many situations an ideal host for production of recombinant proteins, since it generally provides a rapid and economical means to achieve sufficiently high product quantities. LÄS MER

  3. 3. Intracellular Flows and Fluctuations

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Johan Elf; Uppsala universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; mesoscopic; reaction-diffusion; protein synthesis; amino acid; flow; fluctuations; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; Molecular Biotechnology; Molekylär bioteknik;

    Sammanfattning : Mathematical models are now gaining in importance for descriptions of biological processes. In this thesis, such models have been used to identify and analyze principles that govern bacterial protein synthesis under amino acid limitation. LÄS MER

  4. 4. Biomolecular simulations, from RNA to protein : thermodynamic and dynamic aspects

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Biosciences and Nutrition

    Författare :Olof Allnér; Karolinska Institutet.; Karolinska Institutet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The process of transforming the information stored in the DNA of genes into functional RNA molecules and proteins via transcription and translation is the most fundamental process of all known life. Even though these processes involve large macromolecules and dynamics on long time scales they all ultimately rely on atomic level interactions between nucleic acids or amino acids. LÄS MER

  5. 5. Selective ADAR editing and the coordination with splicing

    Detta är en avhandling från Stockholm : Institutionen för molekylärbiologi och funktionsgenomik

    Författare :Annika Källman; Stockholms universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi;

    Sammanfattning : Maturation of precursor messenger RNAs (pre-mRNA) in eukaryotes includes processes like capping, 3’ end formation and splicing. Some premRNAs undergo an additional process called RNA editing where a single nucleotide is modified to generate a new nucleotide identity. LÄS MER