Sökning: "protoporphyrin IX"

Visar resultat 21 - 25 av 26 avhandlingar innehållade orden protoporphyrin IX.

  1. 21. Structural studies on the extracellular flavocytochrome cellobiose dehydrogenase from Phanerochaete chrysosporium

    Författare :Martin Hällberg; Andrea Mattevi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; cellobiose dehydrogenase; flavocytochrome; hydride transfer; radical mechanism; X-ray crystallography; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Biology; with specialization in structural biology; biologi; med inriktning mot strukturbiologi;

    Sammanfattning : Microorganisms that degrade lignocellulose play an important role in maintaining the global carbon cycle. Under cellulolytic conditions, the fungus Phanerochaete chrysosporium produces an extracellular flavocytochrome, cellobiose dehydrogenase (CDH), with a proposed role in lignocellulose degradation. LÄS MER

  3. 22. Non-linear Optical Microscopy and Spectroscopy for Biomedical Studies

    Författare :Stina Guldbrand; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Two-Photon Excitation Microscopy; Fluorescence Correlation Spectroscopy; Multiphoton Luminescence; Human Skin; Gold nanoparticles;

    Sammanfattning : This thesis is based on the application of non-linear optical microscopy and spectroscopy techniques within biomedical research. Non-linear optical microscopy gives the possibility of exciting fluorophores using near infrared light. LÄS MER

  4. 23. Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery

    Författare :Vladimir Kirejev; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Photodynamic therapy; PDT enhancement; Nitric oxide; NO-based PDT; Targeted drug delivery; Galectin-3; mTHPP; Cyclodextrin; CD-mTHPP conjugate; PpIX AuNP combination; Two-photon microscopy; FLIM; Cell phototoxicity; Ex vivo skin;

    Sammanfattning : The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. This thesis explores different nanosystems with aim to improve PDT focusing on spectroscopic and ex vivo studies. LÄS MER

  5. 24. Fluorescence Spectroscopy for Quantitative Demarcation of Glioblastoma Using 5-Aminolevulinic Acid

    Författare :Neda Haj-Hosseini; Karin Wårdell; Göran Salerud; Peter E Andersen; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Total resection of glioblastoma, the highly malignant brain tumor, is difficult to accomplish due to its diffuse growth and similarity to the surrounding brain tissue. A total resection is proven to increase patient survival. LÄS MER

  7. 25. Elucidation of thioredoxin reductase 1 as an anticancer drug target

    Författare :William C Stafford; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer constantly finds ways to survive, so we must find new ways to stop it. A major attribute of cancer cells is increased oxidative stress, occurring in the form of reactive oxygen species (ROS). Basal ROS generation commonly occurs in all types of cells and is essential for normal cellular growth and function. LÄS MER