Sökning: "lung surfactant"

Visar resultat 1 - 5 av 42 avhandlingar innehållade orden lung surfactant.

1. 1. Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia

   Författare :Anna Hogmalm; Göteborgs universitet; []
   Nyckelord :bronchopulmonary dysplasia; transgenic mice; inflammation; lung; interleukin-1; αvβ6 integrin; mmp-9; surfactant;

   Sammanfattning : Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD. LÄS MER

3. 2. Neonatal resuscitation - studies in piglets

   Författare :Rikard Linnér; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Newborn resuscitation; birth asphyxia; cerebral oxygenation; adrenaline; noradrenaline; severe hypoventilation; surfactant; nebulisation; vibrating mesh nebuliser. CPAP; lung deposition; lung distribution.;

   Sammanfattning : Background and aims: “It’s best to start with air” states the current guidelines on the resuscitation of babies at birth. In a piglet model mimicking severe neonatal asphyxia and circulatory arrest, different aspects of resuscitation were investigated (studies I-III). LÄS MER

4. 3. Self-Assembly in Lipid-Protein Systems : Lung Surfactant, Stratum Corneum and Model Membranes

   Författare :Jenny Andersson; Fysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipid self-assembly; lung surfactant; stratum corneum; dehydrin; cholesterol; osmolytes; urea; TMAO; ssNMR; cSAXS;

   Sammanfattning : This thesis explores lipid self-assembly and aims to give a broad picture of self-assembly structures in simple and complex lipid-protein systems. The systems studied are lung surfactant, stratum corneum and simple model membranes. The lung surfactant mixture lines the alveolus in our lungs and stabilises the air- tissue interface. LÄS MER

5. 4. Lung hyaluronan and lung water in the perinatal period

   Författare :Hans Johnsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; antenatal corticosteroids; antenatal terbutaline; hyaluronan; hyperoxia; lung water; perinatal period; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

   Sammanfattning : Hyaluronan is an important component of the lung extracellular matrix, with a high capacity for water immobilization, but information on perinatal changes in the lung hyaluronan concentration and their association with changes in the lung water content is limited. In this study, conducted both in rabbit pups and in human infants, we investigated changes in the hyaluronan concentration and distribution in the lung and in the lung water content after preterm or term birth, and changes produced by common antenatal and postnatal pathological conditions and treatments. LÄS MER

7. 5. Breathing Pattern and Lung Mechanics during Assisted Ventilation Response of Slowly Adapting Pulmonary Stretch Receptors and Effects on Phrenic Nerve Activity in Cats with Normal and Surfactant Depleted Lungs

   Författare :Richard Sindelar; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; slowly adapting pulmonary stretch receptor; phrenic nerve activity; assisted ventilation; surfactant; breathing pattern; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

   Sammanfattning : Different modes of assisted ventilation were investigated in cats before and after lung lavage and after instillation of surfactant. The activity of single units of slowly adapting pulmonary stretch receptors (PSRs) in the vagal nerve and the integrated phrenic nerve activity were recorded. LÄS MER