Sökning: "hematopoietic cells"

Visar resultat 6 - 10 av 332 avhandlingar innehållade orden hematopoietic cells.

  1. 6. Genetic modeling of the Hippo pathway in hematopoietic stem cells

    Författare :Lina Jansson; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cells; hematopoiesis; Hippo pathway; hematopoietic stem cells;

    Sammanfattning : Hematopoiesis is the process of blood formation from a limited pool of hematopoietic stem cells (HSCs). These rare stem cells can both self-renew to maintain the HSC pool, and differentiate to continuously replenish lost blood cells. The mechanisms of HSC regulation are not fully known. LÄS MER

  3. 7. Molecular regulation of hematopoietic stem cells

    Författare :David Bryder; Avdelningen för molekylär hematologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; Haematology; bone marrow transplantation; cytokines; Hematopoiesis; stem cells;

    Sammanfattning : Hematopoietic stem cells (HSCs) are ultimately responsible for the all mature blood cell production. They can primarily be found in the bone marrow (BM) at a low frequency (~0.02%). LÄS MER

  4. 8. Receptor tyrosine kinase c-Kit signalling in hematopoietic progenitor cells

    Författare :Charlotte Edling; Bengt Hallberg; Pontus Aspenström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RTK; c-Kit; MAPK; PI3K; PKC; hematopoietic cells; proliferation; differentiation; apoptosis; Pathology; Patologi;

    Sammanfattning : The receptor tyrosine kinase (RTK) c-Kit is expressed in hematopoietic stem and progenitor cells, mast cells and in several non-hematopoietic tissues. In the hematopoietic system c-Kit and its ligand Steel Factor (SF, aka Stem Cell Factor) are critical for proliferation, survival and differentiation. LÄS MER

  5. 9. Neurogenesis from Neural Stem Cells, Ependymal Cells and Fibroblasts

    Författare :Karthikeyan Devaraju; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adult neurogenesis; stroke; neural stem cells; Lnk; ependymal cells; FoxJ1; cortical reprogramming;

    Sammanfattning : Stroke is a major cause of death and disability around the world. Stroke leads to loss of neurons and also other cells in the brain due to lack of blood supply. Currently no therapies are available to treat stroke-related disability. It has been shown that stroke leads to increased neurogenesis, birth of new neurons, within the brain. LÄS MER

  7. 10. Cytokine Regulation of Hematopoietic Stem Cells and Lymphopoiesis

    Författare :Natalija Buza-Vidas; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; Haematology; Medicin människa och djur ; Medicine human and vertebrates ; lineage commitment; cytokines; lymphopoiesis; extracellulära vätskor; transplantation; hematopoietic stem cells;

    Sammanfattning : Large numbers of blood cells need to be continuously replaced in order to sustain the crucial functions of the immune system, oxygen transport and blood clotting. The large diversity of cell types required to maintain the integrity of the blood system are all produced from blood forming or hematopoietic stem cells (HSCs). LÄS MER