Sökning: "non-invasive molecular techniques"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden non-invasive molecular techniques.

1. 1. Population History and Non-invasive Monitoring : Use of low copy number DNA in Conservation Genetics

   Författare :Øystein Flagstad; Ettore Randi; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; genetic tagging; immigration; loss of genetic variability; non-invasive molecular techniques; population decline; Swayne’s hartebeest; wolf; wolverine; Biologi; Biology; Biologi; ekologisk botanik; Ecological Botany;

   Sammanfattning : Conservation genetics research is increasingly becoming an integrated part of the management of small and endangered populations. In this thesis I developed tools for genetic analysis of low copy number sources of DNA, such as old teeth from museum specimens as well as field-collected faeces and urine. LÄS MER

3. 2. Development of radiometal-based labelling techniques and tracers for non-invasive molecular imaging

   Författare :Emma Jussing; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Metallic radionuclides, radiometals, have an important role in nuclear medicine. Their straightforward coordination radiochemistry allows for a large variety of applications. LÄS MER

4. 3. Conservation Genetics of Scandinavian Wolverines

   Författare :Eva Hedmark; Hans Ellegren; Lisette Waits; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; carnivores; conservation; genetic monitoring; molecular sexing; non-invasive genetic techniques; parentage analysis; tanning; Genetik; Gulo gulo; Genetics; Genetik;

   Sammanfattning : In this thesis, genetic methods for individual identification and sex determination of wolverines from non-invasive samples were developed and applied in genetic monitoring of Scandinavian wolverine populations. Paternity and mating system of wolverines were studied by combining genetic analysis with telemetry data. LÄS MER

5. 4. Dried blood sampling and digital readout to advance molecular diagnostics

   Författare :Johan Björkesten; Ulf Landegren; Björn Högberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; molecular diagnostics; dried blood sample; DBS; digital readout; digital enumeration; DNA detection methods; proximity extension assay; protein stability; genotyping; rare mutations; cell free DNA; multiplex protein measurement.; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : A drastically increased capacity to measure large sets of molecular features in numerous patient samples in great detail will be required to fulfill the vision of precision medicine and wellness, which may characterize molecular diagnostics in the 21st century. Also sampling procedures need a renaissance to permit continuous sampling at population levels at reasonable cost. LÄS MER

7. 5. Precision molecular spectroscopy in the near- and mid-infrared using frequency comb-based Fourier transform spectrometers

   Författare :Adrian Hjältén; Aleksandra Foltynowicz; Ove Axner; Adam Fleisher; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; optical frequency comb; molecular spectroscopy; Fourier transform spectrometer; high resolution; mid-infrared; line list; double-resonance spectroscopy; difference frequency generation; fysik; Physics;

   Sammanfattning : Absorption spectroscopy is a powerful scientific tool for non-invasive and remote sensing applications ranging from atmospheric monitoring to astrophysics. In spectroscopic detection schemes it is necessary to have spectral models for any molecular species to be detected or quantified. LÄS MER