Sökning: "Spinal Root"

Visar resultat 6 - 10 av 67 avhandlingar innehållade orden Spinal Root.

  1. 6. Spinal cord injury : mechanical and molecular aspects

    Författare :Anna Josephson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Spinal cord; syringomyelia; MRI; fMRI; neurotrophin; Nogo; Nogo receptor; regulation;

    Sammanfattning : Traumatic spinal cord injury leads to full or partial paralysis and loss of sensation below the level of injury. The annual incidence of spinal cord injury in the United States is 3-5 per 100,000 and in Sweden is 1.5-2 per 100,000. This translates to 11,000 new cases of traumatic spinal cord injury in the US and 150 in Sweden each year. LÄS MER

  3. 7. Diagnostic and therapeutic strategies following spinal cord and brachial plexus injuries

    Författare :Amar Karalija; Mikael Wiberg; Zhongyu John Li; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spinal cord injury; brachial plexus injury; acetyl-L-carnitine; N-acetyl-cysteine; MRI; motoneurons; anatomi; Human Anatomy;

    Sammanfattning : Traumatic injuries to the spinal cord and brachial plexus induce a significant inflammatory response in the nervous tissue with progressive degeneration of neurons and glial cells, and cause considerable physical and mental suffering in affected patients. This thesis investigates the effects of the antioxidants N-acetyl-cysteine (NAC) and acetyl-L- carnitine (ALC) on the survival of motoneurons in the brainstem and spinal cord, the expression of pro-apoptotic and pro-inflammatory cell markers, axonal sprouting and glial cell reactions after spinal hemisection in adult rats. LÄS MER

  4. 8. Studies on pain-related messengers and receptors in dorsal root ganglia and spinal cord

    Författare :Malin Rydh-Rinder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pain is the most common reason why people seek medical advice. A large group of patients suffering from so-called neuropathic pain, due to injury to the nervous system itself, is often not helped by the currently available therapies. Classical analgesic drugs, such as opioids and non-steroidal anti-inflammatory drugs, may have severe side effects. LÄS MER

  5. 9. Surgery for ulnar nerve compression at the elbow : Focusing on factors influencing outcome

    Författare :Alice Giöstad; Erika Nyman; Lars Dahlin; Gustav Andersson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ulnar nerve compression; Simple decompression; Nerve transposition; PROM; Pain; Return to work; Spinal nerve root;

    Sammanfattning : Ulnar nerve compression at the elbow (UNE) is a common peripheral nerve compression disorder in the upper limb. The literature regarding surgical outcome is inconclusive. LÄS MER

  7. 10. Regulation of CGRP expression in rat spinal motoneurons

    Författare :Fredrik Piehl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :immunohistochemistry; in situ hybridization; motoneuron; axotomy; peptides; CGRP; trophic factor; FGF; IGF; BDNF; CNTF; GAP-43; cell culture; plasticity; mRNAregulation; regeneration;

    Sammanfattning : The normal distribution and lesion-induced changes in the expression of neuropeptides and growth-related proteins, with special reference to calcitonin gene-related peptide (CGRP),were studied in the motor system of the rat. In addition, factors that influence the expression of CGRP in motoneurons were identified. LÄS MER