Sökning: "IGF"
Visar resultat 1 - 5 av 303 avhandlingar innehållade ordet IGF.
1. Insulin and IGF-I in type 1 diabetes
Sammanfattning : Patients with type I diabetes have alterations in the GH/IGF system with reduced levels of circulating IGF-I, as well as other disturbances in the components of the IGF system.Alterations of both local and circulating IGF-I and its binding proteins (IGFBPs) have been associated with metabolic and vascular manifestations of diabetes and also with atherosclerosis. LÄS MER
2. Early growth, retinopathy of prematurity and insulin-like growth factors in preterm infants
Sammanfattning : Aims:Paper I: To perform measurements of the lower leg length (LLL) in preterm infants, compare and evaluate handling error and precision of two instruments, and estimate the time required to show growth.Paper II-IV: To investigate whether low postnatal levels of serum IGF-I are associated with abnormal retinal vessel development. LÄS MER
3. Early effects of castration therapy in non-malignant and malignant prostate tissue
Sammanfattning : Early Effects of Castration Therapy in Non-malignant and Malignant Prostate Tissue BACKGROUND. Androgen ablation, the standard treatment for advanced prostate cancer, results in increased apoptosis, decreased cell proliferation and subsequent involution of the prostate gland. LÄS MER
4. Pathophysiological Mechanisms and Diagnostic Markers in Alzheimer’s Disease
Sammanfattning : Alzheimer’s disease (AD), the most common cause of dementia, is a growing concern. As the life expectancy increases across the globe, the number of affected people is estimated to reach 100 million by 2050. LÄS MER
5. Effects of GH and liver-derived IGF-I on growth and metabolism
Sammanfattning : Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. LÄS MER