Sökning: "Spinal Root"

Visar resultat 16 - 20 av 67 avhandlingar innehållade orden Spinal Root.

  1. 16. Swimming with the current : Fictive locomotion reveals subtle phenotypes in the zebrafish locomotor network

    Författare :Harmen Kornelis Koning; Henrik Boije; David McLean; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dmrt3a; wt1a; spinal cord; Mauthner cell; neural development; locomotor network; zebrafish;

    Sammanfattning : Neural networks are the functional building blocks of the central nervous system. To better understand how these networks develop and operate, we turned to the zebrafish locomotor network, with a focus on subtypes of interneurons expressing dmrt3a and wt1a. LÄS MER

  2. 17. Spinal Cord Processing of Sensory Information: Spatial Organization and Adaptive Mechanisms

    Författare :Anders Levinsson; Malmö Diagnostisk radiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; transplantatioin; pain; sensorimotor; plasticity; reflex; neuropsykologi; neurofysiologi;

    Sammanfattning : Principles for sensorimotor transformation and plasticity in the spinal cord and functional repair in the root-avulsed spinal cord were studied. A comparative study confirmed that the nociceptive withdrawal reflex (NWR) system is composed of reflex modules, with each performing a finely tuned transformation of skin sensory input to activity in one muscle. LÄS MER

  3. 18. Experimental spinal cord injury : development of protection and repair strategies in rats

    Författare :Matthias Erschbamer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Spinal cord injury typically results in neurological deficits that can not be reversed, often leaving patients bound to a wheelchair. Current treatment strategies are not very successful. Despite many promising experimental strategies, clinical translation has so far been very limited. LÄS MER

  4. 19. Neuronal tracers for fine caliber spinal primary afferents and their response to peripheral nerve injury

    Författare :H Fredrik Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Rat; Primary afferents; Dorsal root ganglion; Peripheral nerve injury; Spinal cord; Isolectin GSA I-B4; Soybean agglutinin; Cholera toxin B subunit; Horseradish peroxidase; Immunohistochemistry; Neuronal tracing;

    Sammanfattning : The isolectin B4 from Griffonia simplicifolia I (B4) and soybean agglutinin from the plant Glycine max (SBA), have been shown to bind to rat small-diameter dorsal root ganglion (DRG) neurons, and to fibers and presumed terminals in laminae I-II of the spinal cord dorsal horn. In the present thesis, these lectins and/or their horseradish peroxidase (HRP) conjugates, have been investigated in the rat with regard to their usefulness as selective neuronal markers of and axonally transported tracers for somatic and/or visceral spinal primary afferents with fine caliber, including unmyelinated, axons. LÄS MER

  5. 20. Dopaminergic and serotonergic modulation of cellular and locomotor network properties in the lamprey spinal cord

    Författare :Martin Wikström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :5-hydroxytryptamine; Dopamine; Calcium channels; Calcium-dependent potassium channels; Afterhyperpolarization; Membrane potential oscillation; Synaptic transmission; Modulation; Central pattern generator; Locomotion; Spinal cord; Lamprey;

    Sammanfattning : Motor activity is the basis for all behavior. It is therefore important to study the processes generating movement such as the neuronal networks in the spinal cord that generates and controls locomotion. The lamprey is used as a model system for the study of locomotion. LÄS MER