Sökning: "Myoglobin"

Visar resultat 21 - 25 av 27 avhandlingar innehållade ordet Myoglobin.

  1. 21. Identification of disease genes in rare neurological conditions

    Författare :Martin Engvall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is about improving diagnosis and treatment to persons affected by rare diseases. Diagnosis before treatment is a principle often told to medical students. LÄS MER

  3. 22. Alpha-1-microglobulin, heme-binding protein, reductase and antioxidant

    Författare :Maria Allhorn; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reduction; inflammation; chronic ulcers; collagen; low density lipoproteins; Medicin människa och djur ; Medicine human and vertebrates ; antioxidation; heme; hemoglobin; alpha-1-microglobulin; lipocalin;

    Sammanfattning : This thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. LÄS MER

  4. 23. Phytoglobins: Elucidation of Structural, Functional and Practical Features of Non-Symbiotic Plant Hemoglobins

    Författare :Simon Christensen; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemoglobin; Fytoglobin; Hexakoordination; Karaktärisering; Protein design; Rekombinant protein production; Kromatografi; kristallografi; Dimerisering; Protein Dynamik;

    Sammanfattning : Phytoglobins (Pgb) (plant hemoglobins) are heme-containing proteins and less well known in comparison to the mammalian counterparts hemoglobin (Hb) andmyoglobin (Mb). They share the same secondary structure as other globin-related proteins, six to eight α-helices comprising the myoglobin-fold (Mb-fold) with one prosthetic heme moiety per subunit. LÄS MER

  5. 24. Medium-chain alcohol dehydrogenases : studies of novel class I, II, III and IV forms revealing structural, functional, and evolutionary properties of this enzyme system

    Författare :Lars Hjelmqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :alcohol dehydrogenase; isozymes; classes; enzymes; amino acid sequence; enzyme functions; protein variability; evolution Lars Hjelmqvist: Medium-chain alcohol dehydrogenases. Studies of novel class I; II; III and IV forms revealing structural; funct;

    Sammanfattning : Novel forms of alcohol dehydrogenases of classes I, II, III, and IV were characterized. Together with other variants, they give useful information on molecular properties and functions of the alcohol dehydrogenase system. They further illustrate general aspects of protein variability, isozyme formation, and evolution of enzyme functions. LÄS MER

  7. 25. Ventricular fibrillation and defibrillation in patients with implantable cardioverter defibrillators

    Författare :Mikael Runsiö; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ventricular fibrillation; defibrilla~ion; implantable cardioverter defibrillator; haemodynamic; metabolism; hyperaemia; ischaemia; myocardial injury; histamine; neuropeptide 1: noradrenaline; endothelin; histamine; positron emission tomography.;

    Sammanfattning : Since the introduction of the implantable cardioverter defibrillator for humans with malignant ventricular arrhythmias in 1980, over 50, 000 patients world wide have received this device. The implantation procedure is simple and resembles the implantation of an ordinary pacemaker. LÄS MER