Sökning: "Igor Sivaev"

Hittade 1 avhandling innehållade orden Igor Sivaev.

1. 1. Synthesis of functional derivatives of [B12H12]2- anion for boron neutron capture therapy, radiodiagnostics and radioimmunotherapy

   Författare :Igor Sivaev; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

   Sammanfattning : Functional derivatives of dodecahydro-closo-dodecaborate anion [B12H12]2- are potential candidates for medical application in boron neutron capture therapy for cancer and as linkers for the introduction of radiohalogen label into biomolecules for radioimmunodiagnostics and radioimmunotherapy.In this study, new approaches for the synthesis of functional derivatives of the closo-dodecaborate anion were developed and a series of novel functional derivatives were prepared. LÄS MER