Sökning: "Ida Alenkvist"

Hittade 1 avhandling innehållade orden Ida Alenkvist.

1. 1. Epac2 signaling at the β-cell plasma membrane

   Författare :Ida Alenkvist; Anders Tengholm; Olga Göransson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-cell; insulin secretion; cAMP; Ca2 ; Epac; Rap; exocytosis; sulfonylurea; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Secretion of appropriate amounts of insulin from pancreatic β-cells is crucial for glucose homeostasis. The β-cells release insulin in response to glucose and other nutrients, hormones and neurotransmitters, which trigger intracellular signaling cascades, that result in exocytotic fusion of insulin-containing vesicles with the plasma membrane. LÄS MER