Sökning: "exocytosis"

Visar resultat 1 - 5 av 137 avhandlingar innehållade ordet exocytosis.

  1. 1. Nature of Large Vesicle Exocytosis in Pancreatic β-cells: Release of ATP and GABA

    Författare :Jovita Karanauskaite; Islet cell physiology; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; LDCV; Insulin; exocytosis; Compound Exocytosis; Calcium;

    Sammanfattning : Several high resolution electrophysiological techniques such as measurements of cell membrane capacitance and amperometry are used to detect exocytotic events. A novel method was developed in this study based on the expression of P2X2 receptor channel in secreting cells. LÄS MER

  3. 2. Mechanisms of insulin exocytosis and release

    Författare :Sebastian Barg; Islet cell physiology; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ClC-3; electrophyiology; confocal microscopy; calcium channel; readily releasable pool; exocytosis; insulin; diabetes; green fluorescent protein; Physiology; Fysiologi;

    Sammanfattning : Endocrine cells as well as neurons release their hormones and transmitters by regulated exocytosis. In the pancreatic B-cell, stimuli like glucose initiate biochemical and electrical processes that culminate in influx of Ca2+, which then triggers exocytosis of insulin-containing granules. LÄS MER

  4. 3. New Electrochemical Tools to Study Exocytosis

    Författare :Joakim Wigström; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; amperometry; QCM-D; micro electrode array; large dense core vesicles; chromaffin cells; PC-12 cells; microelectrode; exocytosis; electrochemical cytometry; electrochemical imaging; acetylcholine; endocytosis; nanoparticles; enzyme biosensor; microfabrication;

    Sammanfattning : The work described in this thesis has the focus on the development of new analytical tools to study processes related to cellular secretion (exocytosis) in cell models. Four novel techniques were developed, allowing new ways to study processes related to exocytosis, and gain previously unattainable knowledge. LÄS MER

  5. 4. Exocytosis in insulin secreting cells - role of SNARE-proteins

    Författare :Jenny Vikman; Diabetes - öcellsexocytos; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; calcium channel; cAMP; syntaxin 1; SNAP-25; SNARE; exocytosis; Insulin secretion; pancreatic beta-cells;

    Sammanfattning : Type 2 diabetes is marked by deterioration in pancreatic β-cell function. SNARE-proteins are crucial for the fusion of insulin granules with the plasma membrane, a prerequisite for insulin secretion. LÄS MER

  7. 5. Molecular and physiological regulation of adiponectin exocytosis in white adipocytes

    Författare :Ali Komai; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipocytes; white adipocytes; adiponectin secretion; exocytosis; stimulus-secretion coupling; obesity; diabetes;

    Sammanfattning : .... LÄS MER