Sökning: "Caco-2 cell model"
Visar resultat 11 - 15 av 32 avhandlingar innehållade orden Caco-2 cell model.
11. Provitamin A Carotenoids in Orange-Fleshed Sweet Potato
Sammanfattning : Vitamin A deficiency is a major nutritional disorder in a large number of developing countries. The disorder is mainly caused by an inadequate intake of preformed vitamin A and provitamin A carotenoids from the diet. It is also recognized that vitamin A deficiency and iron deficiency tend to coexist in many population groups. LÄS MER
12. Improving vitamin A nutrition in low-income countries. In vitro bioaccessibility of provitamin A carotenoids in biofortified orange-fleshed sweet potato
Sammanfattning : Vitamin A deficiency is a major nutritional disorder in a large number of low-income countries that is caused by an inadequate intake of preformed vitamin A and provitamin A carotenoids in the diet. The objective of the present thesis was to evaluate orange-fleshed sweet potato (OFSP) as a biofortified food source of provitamin A carotenoids with a potential to be included in a diet for alleviating vitamin A deficiency. LÄS MER
13. Gliadin-Blocking Peptides In vitro assessment of their potential to alleviate celiac disease development
Sammanfattning : This thesis work aimed to investigate the potential of synthetic peptides as agents to block wheat prolamins (gliadins) that trigger the development of symptoms in celiac disease. The first step of this investigation included selection and synthesis of peptides with high affinity to gliadins and assessment of the potential of these so-called blocking peptides to limit gliadin reactivity in vitro. LÄS MER
14. The cross-talk of iron and ascorbate -Complexation and intracellular regulation of transport in human enterocytes
Sammanfattning : Iron deficiency is a serious health issue in developing countries and also in vulnerable groups of the industrialized world. There are several ways to address this issue. The present approach was to learn more about the basic mechanisms of iron uptake in the presence of ascorbate, one of the best enhancers of iron absorption. LÄS MER
15. Malting of Barley for healthy foods. Optimal conditions for phytate removal and preservation of ?-glucan, in vitro iron availability and degradation of phytate and ?-glucan during in vitro digestion
Sammanfattning : A high concentration of phytate (myo-inositol hexaphosphate) in cereals is known to impair absorption of dietary minerals. The aim of this work was to optimize a malting procedure to degrade phytate and/or increase phytase activity in barley to improve iron availability and to preserve the content of β-glucan, since β-glucan is associated with health promoting properties and is therefore of nutritional interest. LÄS MER