Sökning: "oil-induced arthritis"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden oil-induced arthritis.

1. 1. Aspects of adjuvants in experimental arthritis and autoimmunity : studies of oil-induced arthritis - a new model of arthritis in rats

   Författare :Sandra Kleinau; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

3. 2. Cytokine regulation in rodents with experimental arthritis

   Författare :Åsa Boström Müssener; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :collagen-induced arthritis; oil-induced arthritis; IL-2; IL-4; TNFa; IFNy; TGFß;

   Sammanfattning : The general aim of this project has been to try to elucidate the mechanisms behind induction of arthritis by using in situ hybridization and immunohistochemical methods to analyse the dynamics of the cytokine network in vivo, in the peripheral Iymphoid system and in the joints of rodents with collagen-induced arthritis (CIA)and oil-induced arthritis (OIA). We first examined the kinetics of cytokine gene expression in vivo, in the draining Iymph nodes of DA rats following immunization with rat type II collagen (RCII) emulsified in Freund's incomplete adjuvant oil (FIA) or with only FIA, which are regimens that induce CIA and OIA, respectively. LÄS MER

4. 3. Tissue destruction in arthritis : experimental studies

   Författare :Esbjörn Larsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Destruction of joint cartilage and bone is one of the most serious consequences of chronic arthritis. Clinically, the standard assessment of joint destruction is performed by radiography. LÄS MER

5. 4. Genetic dissection of experimental arthritis in the DA rat

   Författare :Liselotte Bäckdahl; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :RA; Experimental arthritis; QTL; congene; Aplec; > human association;

   Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting peripheral joints. Persistent inflammation causes cartilage deterioration with severe joint deformations as a consequence. The etiology is largely unknown but complex interactions between genetic and environmental factors contribute to the disease. LÄS MER

7. 5. Immunologic and genetic studies of rat adjuvant-induced arthritis

   Författare :Åsa Jansson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :arthritis; autoimmunity; adjuvant; incomplete Freund s adjuvant; squalene; quantitative trait locus;

   Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with a multifactorial and largely unknown etiology. It is influenced by both environmental and genetic factors, and understanding of disease mechanisms and identification of disease-causing genes is hampered by the complex and polygenic nature of the disease. LÄS MER