Sökning: "mtDNA"
Visar resultat 1 - 5 av 111 avhandlingar innehållade ordet mtDNA.
1. Molecular and structural studies of proteins required for mitochondrial DNA maintenance
Sammanfattning : Mitochondria are membrane-bound organelles that produce the majority of ATP used to drive metabolic processes in eukaryotic cells. A unique feature of mitochondria is the existence of a separate mitochondrial DNA (mtDNA), which codes for thirteen proteins needed for oxidative phosphorylation (OXPHOS). LÄS MER
2. Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity
Sammanfattning : Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated with defects in the oxidative phosphorylation in mitochondria. LÄS MER
3. Analysis of the origin and spread of the domestic dog using Y-chromosome DNA and mtDNA sequence data
Sammanfattning : The domestic dog was probably the first domesticated animal, and the only one to spread to all continents in ancient times. The dog is one of the most phenotypically diverse animals, a result of human selection throughout dog history. LÄS MER
4. Regulation of Human Mitochondrial DNA Replication and Transcription
Sammanfattning : Mitochondria are organelles in eukaryotic cells, which through oxidative phosphorylation (OXPHOS) produce most of the ATP used to drive cellular processes. The organelle contains its own genetic material, mitochondrial DNA (mtDNA), which encodes 13 key components of the OXPHOS machinery. LÄS MER
5. Analysis of domestic dog mitochondrial DNA sequence variation for forensic investigations
Sammanfattning : The first method for DNA analysis in forensics was presented in 1985. Since then, the introduction of the polymerase chain reaction (PCR) has rendered possible the analysis of small amounts of DNA and automated sequencing and fragment analysis techniques have facilitated the analyses. LÄS MER