Sökning: "mrnp"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet mrnp.

  1. 1. Characterization of RNA exosome in Insect Cells : Role in mRNA Surveillance

    Författare :Viktoria Hessle; Neus Visa; Maria Carmo-Fonseca; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell nucleus; nuclear bodies; mRNA surveillance; cotranscriptional assembly; Rrp6; Rrp4; mRNP; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : The exosome, an evolutionarily conserved protein complex with exoribonucleolytic activity, is one of the key players in mRNA quality control. Little is known about the functions of the exosome in metazoans. We have studied the role of the exosome in nuclear mRNA surveillance using Chironomus tentans and Drosophila melanogaster as model systems. LÄS MER

  2. 2. Cytoplasmic mRNP particles in dormant and developing artemia embryos

    Författare :Mats Lake; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : In dormant cryptobiotic embryos of Artemia there is a stored pool of messenger RNA (mRNA) associated with the endoplasmic reticulum. Upon resumption of the embryos this latent mRNA is activated and used in the protein synthesis. LÄS MER

  3. 3. A Y-box protein/RNA helicase complex links mRNP assembly on the gene to mRNA translation

    Författare :Dmitri Nashchekin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immediately upon transcription, messenger RNA molecules become associated with proteins to form ribonucleoprotein (RNP) complexes, usually called mRNP particles. The mRNPs are the actual targets for regulation and dictate the fate of an mRNA in the gene expression pathway. LÄS MER

  4. 4. Molecular Cloning and Functional Characterization of Factors Involved in Post-transcriptional Gene Expression

    Författare :Shao-Bo Jin; Lars Wieslander; Maria Carmo-Fonseca; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; gene expression; pre-mRNA processing; pre-rRNA processing; Molecular biology; Molekylärbiologi;

    Sammanfattning : Gene expression in the eukaryotic cell is a fundamental cellular process, which consists of several distinct steps but extensively coupled to each other. From site of transcription in the nucleus to the cytoplasm, both mRNA and rRNA are associated with a proper set of proteins. LÄS MER

  5. 5. Transcription and transport of a messenger RNP particle : novel regulatory mechanisms

    Författare :Karin Kylberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In all living cells gene expression is a central process that involves several steps, including transcription, processing, transport and translation. A fine-tuning of these events is a pre-requisite for proper cellular function. LÄS MER