Sökning: "Maria Carmo-Fonseca"

Hittade 2 avhandlingar innehållade orden Maria Carmo-Fonseca.

  1. 1. Characterization of RNA exosome in Insect Cells : Role in mRNA Surveillance

    Författare :Viktoria Hessle; Neus Visa; Maria Carmo-Fonseca; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell nucleus; nuclear bodies; mRNA surveillance; cotranscriptional assembly; Rrp6; Rrp4; mRNP; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : The exosome, an evolutionarily conserved protein complex with exoribonucleolytic activity, is one of the key players in mRNA quality control. Little is known about the functions of the exosome in metazoans. We have studied the role of the exosome in nuclear mRNA surveillance using Chironomus tentans and Drosophila melanogaster as model systems. LÄS MER

  2. 2. Molecular Cloning and Functional Characterization of Factors Involved in Post-transcriptional Gene Expression

    Författare :Shao-Bo Jin; Lars Wieslander; Maria Carmo-Fonseca; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; gene expression; pre-mRNA processing; pre-rRNA processing; Molecular biology; Molekylärbiologi;

    Sammanfattning : Gene expression in the eukaryotic cell is a fundamental cellular process, which consists of several distinct steps but extensively coupled to each other. From site of transcription in the nucleus to the cytoplasm, both mRNA and rRNA are associated with a proper set of proteins. LÄS MER