Sökning: "leukemia antisense cell cycle differentiation hematopoiesis p16 p53 tumor suppressor genes RB oligonucleotides Haematology extracellular fluids Hematologi extracellulära vätskor"

Hittade 1 avhandling innehållade orden leukemia antisense cell cycle differentiation hematopoiesis p16 p53 tumor suppressor genes RB oligonucleotides Haematology extracellular fluids Hematologi extracellulära vätskor.

1. 1. On the role of the retinoblastoma tumor suppressor gene in hematopoietic differentiation

   Författare :Gösta Bergh; Helsingborg Kliniska Vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antisense; leukemia; cell cycle; differentiation; hematopoiesis; p16; p53; tumor suppressor genes; RB; oligonucleotides; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

   Sammanfattning : The aim of this study was to investigate the role of some tumor suppressor gene products (with emphasis on the retinoblastoma suppressor gene product) in the regulation of differentiation and proliferation in leukemic and normal hematopoietic cells. For this purpose, the expression of the tumor suppressor genes RB, p53 and p16 were artificially altered. LÄS MER