Sökning: "islets"

Visar resultat 26 - 30 av 330 avhandlingar innehållade ordet islets.

  1. 26. Mechanisms underlying lipotoxicity and glucotoxicity in pancreatic islets

    Författare :Sandra Meidute; Islet cell physiology; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hormone secretion; cell stress; Pancreatic beta-cell; cellular signalling; GPR40; diabetes;

    Sammanfattning : Although it has been known for many years that long-term exposure of pancreatic islets to a high level of free fatty acids (FFA) or glucose negatively modulates islet hormone release, the identities of signals mediating these effects are not yet fully clarified. The overall objective of this study was to investigate signal transduction pathways involved in FFA- and glucose-exerted effects on beta-cell function during both short-term as well as long-term exposure. LÄS MER

  3. 27. Imaging Islets of Langerhans by Positron Emission Tomography : Quantification of Beta-Cell Mass in the Native Pancreas and the Islet Graft

    Författare :Olof Eriksson; Anders Sundin; Olle Korsgren; Bengt Långström; Bo Nilsson; Håkan Ahlström; Habib Zaidi; Uppsala universitet; []
    Nyckelord :Positron Emission Tomography; [18F]FDG; dihydrotetrabenazine; Islet transplantation; IBMIR; beta-cell mass; MEDICINE; MEDICIN;

    Sammanfattning : Type 1 and 2 Diabetes Mellitus are a growing health problem throughout the world. There is an increasing  need for methodologies, which are both reliable and non-invasive to measure the amount of insulin-producing tissue (Beta-cell mass, or BCM), as well as rapidly quantify changes in the BCM due to the onset of disease, beta-cell replacement therapy, or other treatments. LÄS MER

  4. 28. Regulation of phospholipid metabolism in isolated pancreatic islets

    Författare :Anders Hallberg; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 29. Functional Impairments of Islets Transplanted into the liver

    Författare :Joey Lau; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 30. Lysosomes and Intracellular Degradation of Insulin in Pancreatic Islets

    Författare :Monica Sandberg; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER