Sökning: "genome diversity"

Visar resultat 21 - 25 av 179 avhandlingar innehållade orden genome diversity.

  1. 21. Genome evolution of a bee-associated bacterium

    Författare :Andrea García-Montaner; Siv Andersson; Matthias Horn; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacterial evolution; Genomics; Symbiosis; Honeybees; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : The use of large-scale comparative genomics allows us to explore the genetic diversity and mechanisms of evolution of related organisms. This thesis has focused on the application of such approaches to study Lactobacillus kunkeei, a bacterial inhabitant of the honeybee gut.We produced 102 novel complete genomes from L. LÄS MER

  3. 22. Genome-plasticity and adaption in Helicobacter pylori

    Författare :Christina Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Helicobacter pylori is a gastric bacterial pathogen that infects an estimated half. of the human population. The infection is primarily acquired during early childhood and causes a persistent infection that is usually not eradicated by the host immune system. Although most infected individuals. LÄS MER

  4. 23. Genetic and antigenic diversity in Pneumocystis jirovecii

    Författare :Jessica Beser; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pneumocystis jirovecii is a human specific, atypical fungus with a worldwide distribution that causes disease in immunocompromised individuals. The fungus proliferates in the lungs where it binds to epithelial alveolar cells, provoking severe pneumonia, denoted pneumocystis pneumonia (PCP). LÄS MER

  5. 24. Detecting Signatures of Selection within the Dog Genome

    Författare :Abhirami Ratnakumar; Matthew Webster; Kerstin Lindblad-Toh; Greg Barsh; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dog; evolution; domestication; PRDM9; recombination; positive selection; selective sweep;

    Sammanfattning : Deciphering the genetic basis of phenotypic diversity is one of the central aims of biological research. Domestic animals provide a unique opportunity for making substantial progress towards this goal. LÄS MER

  7. 25. Exploring the diversity and evolution of giant viruses in deep sea sediments using genome-resolved metagenomics

    Författare :Disa Bäckström; Thijs J. G. Ettema; Anna J. Szekely; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metagenomics; binning; viruses; NCLDV; Megavirales; viral evolution.;

    Sammanfattning : Viruses are the most abundant biological entities on this planet, which is impressive considering that they are completely dependent on their hosts for reproduction. Recently the idea of what viruses are has changed dramatically, with the discovery of giant viruses that belong to the Nucleocytoplasmic Large DNA Viruses (NCLDV), such as Mimiviridae, Marseilleviridae, and the proposed families Pandoraviruses, and Pithoviruses. LÄS MER