Sökning: "ectopic expression"

Visar resultat 16 - 20 av 99 avhandlingar innehållade orden ectopic expression.

  1. 16. Regulation and function of the Mad/Max/Myc network during neuronal and hematopoietic differentiation

    Författare :Anne Hultquist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Myc; Mad1; neuroblastoma; hematopoiesis; phorbol ester; retinoic acid; interferon-g; TGF-b; differentiation.; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : The Mad/Max/Myc transcription factor network takes part in the control of vital cellular functions such as growth, proliferation, differentiation and apoptosis. Dimerization with the protein Max is necessary for the Myc-family of oncoproteins and their antagonists, the Mad-family proteins, to regulate target genes and carry out their intended functions. LÄS MER

  3. 17. Forkhead Genes in Mammalian Development

    Författare :Henrik Landgren; Göteborgs universitet; []
    Nyckelord :Development; Forkhead;

    Sammanfattning : This thesis concerns aspects of Forkhead gene biology and it’s relation to mammalian development. Genes from three subclasses are discussed, Foxj3, Foxf1 and f2, and Foxe3. LÄS MER

  4. 18. Connecting viral oncoproteins to microRNA, autophagy and metabolism in Merkel cell carcinoma

    Författare :Satendra Kumar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Merkel cell carcinoma (MCC) is an aggressive type of skin cancer. Around 80% of MCCs harbor an integrated Merkel cell polyomavirus (MCPyV) genome with a mutation in the large T antigen (LT) gene, leading to expression of truncated LT. It is evident that the viral truncated LT and small T antigen (sT) play important roles in MCC tumorigenesis. LÄS MER

  5. 19. Characterization of non-coding RNAs in cancer

    Författare :Per Johnsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : While originally though to only code for proteins, it now stands clear that RNA is a multifunctional molecule involved in a great variety of molecular processes. Recent advances in genome-wide platforms have revealed underappreciated roles of non-protein coding RNAs (ncRNAs). LÄS MER

  7. 20. Regulation and function of Pax-6 during head and eye development in Drosophila melanogaster

    Författare :Linn Jacobsson; Åsa Rasmuson-Lestander; Uwe Walldorf; Umeå universitet; []
    Nyckelord :molekylärbiologi; Molecular Biology;

    Sammanfattning : In Drosophila melanogaster, eyeless and twin of eyeless have important function during eye development. Mutants of both genes give a variety of eye and head phenotypes with the strongest being almost headless meaning that they lack all structures derived from the eye-antennal disc. LÄS MER