Sökning: "colon crypt"

Visar resultat 11 - 12 av 12 avhandlingar innehållade orden colon crypt.

1. 11. The antiproliferative role of the liver X receptors in breast and colorectal cancer

   Författare :Lise-Lotte Vedin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The liver X receptors (LXRα and LXRβ) are members of the nuclear receptor superfamily of ligand activated transcription factors and have functions as regulators of lipid and glucose metabolism, as well as inflammatory response. In recent years, several reports have demonstrated an important role of LXRs in the control of cell proliferation. LÄS MER

3. 12. Regulation of survival and proliferation of human intestinal epithelial cells by leukotriene D4

   Författare :Sailaja Paruchuri; Malmö Experimentell patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rac; General pathology; pathological anatomy; Patologi allmän ; patologisk anatomi; PI3K; CREB; p90RSK; Erk-1 2; PKC; inflammation; migration apoptosis; proliferation; LTD4; cell survival;

   Sammanfattning : The pro-inflammatory mediator, Leukotriene D4 (LTD4) is a product of arachidonic acid cascade and has been implicated in asthma and inflammatory bowel diseases. Prolonged inflammatory conditions like ulcerative colitis increases the risk for the development of cancer and the factors that induce the chronic immune response remain uncertain. LÄS MER