Sökning: "colon crypt"
Visar resultat 6 - 10 av 12 avhandlingar innehållade orden colon crypt.
6. Paracellular permeability of intestinal epithelia.An in vivo study
Sammanfattning : Aim: Investigate the importance of paracellular transport of water and solutes during physiological and pathophysiological conditions. Methods: The transport of small water-soluble inert permeability markers, was studied in jejunum and colon in anesthetized rats and cats during normal conditions and during exposure to cholera toxin (CT) and deoxycholic acid (DCA). LÄS MER
7. Deciphering cell motility and spatial sensing of intestinal cell types using an ex vivo intestinal model
Sammanfattning : The intestine is a highly organized tissue with two distinct regions: the crypt and the villus. When stem cells divide at the crypt bottom, half of their progeny migrates upwards towards the villus, where they differentiate into various cell types, including the abundant absorptive enterocytes. LÄS MER
8. Gene expression in carcinogenesis
Sammanfattning : It is important to understand the processes of carcinogenesis and to find out which genes are involved . One way to study the process on a molecular basis is to identify differences in gene expression. LÄS MER
9. No guts, no glory : EphB mediated signaling in intestinal stem and progenitor cells
Sammanfattning : The work presented in this thesis is focused on the intestinal stem cell niche, the crypts, and the Eph tyrosine kinase receptors together with their ligands that are expressed by the crypt epithelial progenitor cells. Two fundamental cellular processes, high turnover coupled to a rapid ordered migration of the newborn cells out from the crypt, characterize the normal intestine. LÄS MER
10. Anti-infectious and anti-inflammatory activities of lactoferrin and fragments thereof
Sammanfattning : Lactoferrin (LF), a major protein present in milk, mucosal secretions and secondary granules of neutrophils, has been suggested to participate in host defense at mucosal surfaces and to mediate anti-inflammatory activities. A pepsin-derived fragment of LF has been shown to contain the antibacterial domain of the protein. LÄS MER