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1. 1. Somatostatin effects on the proteome of human prostate cancer cells

   Författare :Zhaoxu Liu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The transition of prostate cancer from androgen dependent to the therapy resistant androgen independent state, is a large and persistent problem in the clinical management of prostate cancer. The aim of this thesis was to study somatostatin effects on the proteome of prostate cancer cells, to identify differences in protein expression in androgen dependent and androgen independent prostate cancer cells, and to explore possibilities to enhance the somatostatin receptor expression through pre-treatment with sms, 5-aza and TSA (DNA methylation/HDAC inhibitors). LÄS MER