Sökning: "Panagiotis Papoutsoglou"

Hittade 1 avhandling innehållade orden Panagiotis Papoutsoglou.

1. 1. Regulation of TGFβ signaling by long non-coding RNAs and ADP-ribosylation

   Författare :Panagiotis Papoutsoglou; Aristidis Moustakas; Carl-Henrik Heldin; Peter Zaphiropoulos; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGFβ; signal transduction; long non-coding RNAs; ADP-ribosylation; transcriptional regulation; chromatin remodeling; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Transforming growth factor β (TGFβ) signaling pathways participate in embryonic development and tissue homeostasis and have a dual role in cancer. TGFβ acts as a tumor suppressor that promotes cell cycle arrest and apoptosis at initial stages of tumorigenesis. LÄS MER