Sökning: "Mohamed Sagar"

Hittade 1 avhandling innehållade orden Mohamed Sagar.

1. 1. The importance of the CYP2C19 polymorphism for disposition and effects of omeprazole treatment

   Författare :Mohamed Sagar; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Omeprazole; CYP2C19; H. pylori; gastrin; intragastric pH; vitamin B12;

   Sammanfattning : CYP2C19, catalyzes the metabolism of omeprazole and several other drugs. About 3% of Caucasians are poor metabolizers (PM) of these drugs. The goal of this thesis was to evaluate the importance of CYP2C19 polymorphism for disposition and clinical effects of omeprazole treatment in healthy subjects and in patients with acid related disorders. LÄS MER