Sökning: "Demyelinating Diseases"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden Demyelinating Diseases.

  1. 1. Respiratory burst and severity of demyelinating diseases

    Författare :Natalia Mossberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurologi; immunologi; Guillain-Barré; Multiple sclerosis; respiratory burst;

    Sammanfattning : Multiple sclerosis (MS) and the Guillain-Barré syndrome (GBS) are tissue-specific inflammatory diseases of the central and the peripheral nervous system, respectively. A contemporary analysis infers that these are complex autoimmune disorders. LÄS MER

  3. 2. Mechanisms in inflammatory demyelinating diseases of the nervous system : immunological and methodological aspects

    Författare :Maria Kvarnström; Jan Hillert; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The diseases studied in this thesis, Guillain-Barré Syndrome (GBS), Multiple Sclerosis (MS) and Polyneuropathy associated with monoclonal gammopathy of uncertain significance (PNMGUS), are of autoimmune origin with myelin components as putative auto antigens. T cells are important for the pathogenesis, as well as the cytokine network and autoantibodies. LÄS MER

  4. 3. Immune regulation within the central nervous system and its role in demyelinating diseases

    Författare :Bao-Guo Xiao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) and its animal model, experimental allergic encephalomyelitis (EAE), are diseases of the central nervous system (CNS) characterized by perivascular mononuclear inflammation and oligodendrocyte loss with demyelination. However, it is still not clear whether the pathology in MS and EAE is due to neuroantigen-specific CD4+ T cell-mediated autoimmune responses and/or bystander myelin damage resulting from an inflammatory response. LÄS MER

  5. 4. Genetic dissection of experimental autoimmune neuroinflammatory diseases in rats

    Författare :Ingrid Dahlman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple Sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system (CNS) causing neurological deficits. The disease has a complex etiology comprising multiple unidentified susceptibility genes and environmental influences. LÄS MER

  7. 5. Gene expression of selected immune regulatory molecules in neuroimmunological diseases

    Författare :Wen-Xin Huang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Multiple sclerosis (MS) is an inflammatory, demyelinating disease that is specific to the central nervous system (CNS). Myasthenia gravis (MG) is a disorder of the neuromuscular junction. Both MS and MG are usually considered autoimmune diseases but how the immune system is involved is poorly understood. LÄS MER