Sökning: "Kristina Linder"

Hittade 2 avhandlingar innehållade orden Kristina Linder.

1. 1. Gene expression patterns in human adipose tissue in relation to fat mass and adipose depot

   Författare :Kristina Linder Ekberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Obesity, especially excess amount of abdominal fat, predisposes to a high risk for cardiovascular disease. Cancer cachexia is characterized by a specific loss of white adipose tissue (WAT) and skeletal muscle mass, and is associated with decreased survival and poor response to chemotherapy. LÄS MER

3. 2. Mechanistic studies of a novel inhibitor of the ubiquitin-proteasome system

   Författare :Ellin-Kristina Hillert; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The ubiquitin-proteasome system (UPS) not only maintains cellular proteostasis, but plays an essential role in multiple vital cellular processes, including survival and growth. Proteasomal inhibitors, such as bortezomib, have been shown to have effective anti-cancer properties, verifying the UPS as a viable drug target in cancer treatment. LÄS MER