Sökning: "Kidney Glomerulus"

Visar resultat 16 - 20 av 24 avhandlingar innehållade orden Kidney Glomerulus.

  1. 16. Glomerulopathy in normoalbuminuric adolescents with type 1 diabetes : relations between structure, function, metabolic control and ambulatory blood pressure

    Författare :Torun Torbjörnsdotter; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 1 diabetes; Adolescents; Metabolic control; Kidney morphology; Basement membrane thickness; Foot process width; Kidney function test; Ambulatory blood pressure monitoring;

    Sammanfattning : An increase in the incidence of type 1 diabetes in childhood has been reported in several countries, especially among the youngest children. Although clinically apparent diabetic vascular disease is rare in children and adolescents, 30-40% are at risk of developing nephropathy during their lifetime which may lead to renal failure. LÄS MER

  3. 17. Identification of genes and pathways involved in the development and progression of glomerular diseases

    Författare :Dina Dabaghie; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic kidney disease (CKD) affects millions of people worldwide and is characterized by a reduction in glomerular filtration rate and albuminuria resulting in a gradual loss of kidney function. The high prevalence of the disease, along with the limited treatment options available, makes it a major burden to the health care systems around the world. LÄS MER

  4. 18. Expression profiling of blood vessels in pericyte deficiency and diabetes

    Författare :Jenny Norlin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The kidney glomerulus is essential for the filtration of waste products from the blood into the urine and in controlling the volume and composition of body fluids. Injury to the glomerulus can lead to altered glomerular filtration rate, proteinuria, thickening of the glomerular basement membrane (GBM) and accumulation of mesangial cell matrix. LÄS MER

  5. 19. Characterization of novel podocyte proteins in the glomerular filtration barrier

    Författare :Laleh Sistani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The kidney is considered the most important organ of excretion eliminating the body from metabolic waste products. The nephron is the functional unit of the kidney, composed of a cluster of capillaries named glomerulus, and a tubular system. The blood is filtered in the glomerular capillaries across the glomerular filtration barrier. LÄS MER

  7. 20. Characterization of novel glomerular proteins : role in physiology and disease

    Författare :Ann-Charlotte Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Glomerular damage accounts for the majority of chronic kidney disease cases, the prevalence of which is dramatically escalating worldwide, mainly due to increase in diabetes and associated nephropathy. The costs for treatment of CKD represent an enormous burden to the health care system. LÄS MER