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1. 1. The role of telomerase reverse transcriptase (TERT) in human malignancies : genetic regulation and telomere lengthening-independent oncogenic activities

   Författare :Jingya Yu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Telomerase is a ribonucleoprotein enzyme maintaining telomere length. Telomerase reverse transcriptase (TERT), which acts as a catalytic unit, is tightly repressed in differentiated human cells while activated in cancer cells for telomere lengthening. LÄS MER