Sökning: "Immunization"

Visar resultat 26 - 30 av 267 avhandlingar innehållade ordet Immunization.

  1. 26. B cell fate following immunization : from memory B cells to plasma cells

    Författare :Paola Martínez Murillo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Most approved successful human vaccines induce neutralizing antibody titers maintained above a given threshold for long-term protection against potential pathogen exposure. The pathogens targeted by these vaccines are antigenically stable and the relevant epitopes are immunogenic. LÄS MER

  3. 27. Immunization approaches and molecular signatures for mucosal immunity to primary and recurrent genital herpes

    Författare :Josefine Persson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi;

    Sammanfattning : Genital herpes is most commonly caused by herpes simplex virus type 2 (HSV-2), and is a prevalent sexually transmitted infection worldwide. Despite numerous efforts, there is currently no licensed vaccine against the disease. LÄS MER

  4. 28. The development of a new combined adjuvant vector for mucosal immunization CTA1-DD/ISCOM

    Författare :Anja Helgeby; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CTA1-DD; ISCOM; adjuvants; enzyme; vaccine; B cell; Dendritic cell; T cells;

    Sammanfattning : The CTA1-DD/ISCOMs vector is a rationally designed mucosal adjuvant that was developed to host the distinctive properties of either adjuvant alone or in a combination that hosted additive enhancing effects on mucosal immune responses. Here I demonstrate that CTA1-DD can be incorporated into the ISCOM with greatly augmented immunogenicity of both incorporated and admixed antigen. LÄS MER

  5. 29. Consumer reported digital immunization records : feasibility, applicability, and public health utility in the Canadian context

    Författare :Katherine M Atkinson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Vaccination is one of the most effective public health interventions of all time. Public health programs collect data on Vaccination Coverage (VC) to determine levels of protection and guide resource allocation for further vaccination campaigns but VC data completeness and utility is a challenge in many settings. LÄS MER

  7. 30. Helicobacter pylori infection and immunity. Protection after vaccination and regulation of inflammation in a mouse model

    Författare :Sukanya Raghavan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; formalin-inactivated H. pylori; post-immunization gastritis; cholera toxin; CD4 CD25 regulatory T cells; CpG ODN;

    Sammanfattning : Helicobacter pylori infection is an important cause of chronic active gastritis and peptic ulcer disease and a risk factor for the development of gastric cancer. An attractive strategy in the control of H. pylori infection is the development of a safe and effective therapeutic vaccine. Using a mouse model of H. LÄS MER