Sökning: "ICAM-1"

Visar resultat 16 - 20 av 96 avhandlingar innehållade ordet ICAM-1.

  1. 16. Identification of the susceptibility genes in type 1 diabetes and diabetic nephropathy

    Författare :Jun Ma; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 1 Diabetes; Diabetic Nephropathy; Genetic Association; Single Nucleotide Polymorphism;

    Sammanfattning : Genetic susceptibility plays an important role in the pathogenesis of type 1 diabetes (T1D) and diabetic nephropathy (DN). The present study aims to investigate the association between single nucleotide polymorphisms (SNPs) in candidate genes and DN. LÄS MER

  3. 17. Interferon-alpha based treatment of metastatic malignant melanoma : Effect of immune parameters of importance for monitoring immunotherapy

    Författare :Annika Håkansson; Sten Nilsson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cutaneous malignant melanoma is a rapidly increasing disease. Most patients are cured by surgical excision of their primary tumour, but for patients with metastatic disease the prognosis is still very poor despite various attempts with chemotherapeutic agents, and during the last decade with immunotherapy, using several different biological agents alone or in combination. LÄS MER

  4. 18. Transmigration of Toxoplasma gondii across biological barriers

    Författare :Emily C. Ross; Antonio Barragan; Ildiko Rita Dunay; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Apicomplexa; blood-brain barrier; leukocyte; immune cell; transendothelial migration; cell adhesion molecule; host-pathogen; FAK; integrin; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Toxoplasma gondii is an obligate intracellular parasite that can likely infect all warm-blooded vertebrates, with estimates of up to 30% of the global human population being infected. Although infection with T. gondii is usually asymptomatic or mild, in immunocompromised individuals infection can lead to lethal toxoplasmic encephalitis. LÄS MER

  5. 19. Non-enveloped virus infection probed with host cellular molecules : a structural study

    Författare :Li Xing; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Early steps in virus replication require binding of the virus to its target cell, entry into the cell, and delivery of the viral genome into the cell in order to gain access to the cellular macromolecular synthesis machinery. This infectious process can only be initiated if the virus successfully attaches to a specific receptor on the plasma membrane of the target cell. LÄS MER

  7. 20. Searching for new biomarkers of diabetic nephropathy in Malaysian subjects with type 2 diabetes

    Författare :Norhashimah Abu Seman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : According to the latest National Health and Morbidity Survey reports in year 2011, the prevalence of type 2 diabetes (T2D) in Malaysia has risen to 20.8%, much faster than expected. Of concern, 57% of T2D patients in Malaysia had diabetic nephropathy (DN). LÄS MER