Sökning: "ICAM-1"

Visar resultat 6 - 10 av 96 avhandlingar innehållade ordet ICAM-1.

  1. 6. Functional genetic studies of Psoriasin: a potential biomarker for breast cancer with a poor prognosis

    Författare :Stina Petersson; Göteborgs universitet; []
    Nyckelord :Psoriasin; Breast cancer; Reactive oxidant species; NF-κB; IFNγ; STAT1; ICAM-1; MUC1; CD24;

    Sammanfattning : Breast cancer is the most common malignancy in women. There is a high degree of heterogeneity in breast tumours and they can be divided into subtypes that have different expression pattern and clinical outcome. Ductal Carcinoma in situ (DCIS) is regarded as a precursor of invasive ductal breast cancer. LÄS MER

  3. 7. Vascular and metabolic effects of selective PDE-5 inhibition - clinical and experimental studies

    Författare :Lovisa Sjögren; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; MAPK; phosphodiesterase-5 inhibition; JNK; endothelial cells; E-selectine; VCAM-1; HUVEC; TNFa; ICAM-1; inflammation;

    Sammanfattning : ABSTRACT Vascular and metabolic effects of selective PDE-5 inhibition Clinical and experimental studies Lovisa Sjögren Department of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg Key words: Type 2 diabetes, phosphodiesterase-5 inhibition, inflammation, endothelial cells, HUVEC. TNFα, ICAM-1, VCAM-1, E-Selectin, JNK, MAPK Background: Type 2 diabetes (T2D) patients show impaired glucose metabolism, endothelial dysfunction, chronic low-grade inflammation as well as an increased risk of cardiovascular disease. LÄS MER

  4. 8. Regulation of leukocyte integrin adhesiveness

    Författare :Håkan Hedman; Erik Lundgren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lymphocytes; Cell Adhesion; Integrins; LFA-1; VLA-4; ICAM-1; VCAM-1; Microvesicles; Protein Kinases; Protein Phosphatases;

    Sammanfattning : .... LÄS MER

  5. 9. Pathophysiological Mechanisms and Diagnostic Markers in Alzheimer’s Disease

    Författare :Joakim Hertze; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; mild cognitive impairment; white matter lesions; brain reserve; blood-brain barrier; angiogenesis; neuroinflammation; neurogranin; YKL-40; VEGF; IGF; ICAM-1; VCAM-1;

    Sammanfattning : Alzheimer’s disease (AD), the most common cause of dementia, is a growing concern. As the life expectancy increases across the globe, the number of affected people is estimated to reach 100 million by 2050. LÄS MER

  7. 10. Hand-arm vibration injury - Neurosensory, vascular manifestations, severity grading, and serum biomarkers

    Författare :Eva Tekavec; Arbetsrelaterade besvär i rörelseorganen; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hand-arm vibration injury; Hand-arm vibration syndrome HAVS ; Raynaud s phenomenon; Nerve injury; Seum biomarkers; Vibration perception thresholds; Griffin scores; Stockholm work shop scale; International consensus criteria; Calcitonin gene related peptide; Thrombomodulin; Heat shock protein 27; Caspase 3; ICAM-1; MCP-1; von Willebrand factor; cold intolerance; Small fibre neuropathy; Hand-arm vibrations skada; Nerv skada; Köldintolerans;

    Sammanfattning : .... LÄS MER