Sökning: "transendothelial migration"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden transendothelial migration.

  1. 1. Neutrophil recruitment in H. pylori induced inflammation: characterization of regulatory factors

    Författare :Mikael Innocenti; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; endothelial cells; neutrophils; monocytes; transendothelial; migration; chemokines; cytokines; adhesion molecules inflammation; LPS; CagPAI; VacA;

    Sammanfattning : Helicobacter pylori, a bacterium colonizing the human gastric mucosa, is strongly associatedwith the development of gastric and duodenal ulcers, as well as gastric, adenocarcinoma.Virtually all infected individuals develop active chronic gastritis characterized by a continousinfiltration of neutrophils as well as mononuclear cells. LÄS MER

  3. 2. T cells in colon cancer; migration and effector functions

    Författare :Louis Szeponik; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Treg; CRC; TIL; nSMase2; Transendothelial migration; Unconventional T cells;

    Sammanfattning : Immune cells are recognised as one of the main players in the tumor microenvironment and targeted by many new cancer therapies. Regulatory T cells (Treg) can suppress tumor infiltrating lymphocytes which are associated with a better patient outcome. LÄS MER

  4. 3. Transmigration of Toxoplasma gondii across biological barriers

    Författare :Emily C. Ross; Antonio Barragan; Ildiko Rita Dunay; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Apicomplexa; blood-brain barrier; leukocyte; immune cell; transendothelial migration; cell adhesion molecule; host-pathogen; FAK; integrin; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Toxoplasma gondii is an obligate intracellular parasite that can likely infect all warm-blooded vertebrates, with estimates of up to 30% of the global human population being infected. Although infection with T. gondii is usually asymptomatic or mild, in immunocompromised individuals infection can lead to lethal toxoplasmic encephalitis. LÄS MER

  5. 4. Functions of integrin receptors in extravascular neutrophil migration and respiratory burst

    Författare :Joachim Werr; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adhesion molecules; leukocyte migration; neutrophils; chemotaxis; integrins; respiratory burst; leukocyte extravasation; extracellular matrix; intravital microscopy; acute inflammation;

    Sammanfattning : Leukocytes circulate in the vasculature, but, must leave the blood stream and migrate through the surrounding tissue to exert their protective functions in inflammation. Numerous studies have revealed that intravascular leukocyte-endothelial cell interactions involve functions of adhesion molecules belonging to the selectin and integrin receptor families. LÄS MER

  7. 5. Interaction between extracellular adherence protein (Eap) from Staphylococcus aureus and the human host

    Författare :Axana Haggar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Staphylococcus aureus is one of the most common agents causing bacterial infections in humans and animals. The emergence of extended antibiotic resistance among S. aureus strains as a worldwide epidemic has driven the development of alternative strategies to combat this microorganism. LÄS MER