Sökning: "Multivariate statistical analysis"

Visar resultat 1 - 5 av 114 avhandlingar innehållade orden Multivariate statistical analysis.

  1. 1. Decoding the complex brain multivariate and multimodal analyses of neuroimaging data

    Detta är en avhandling från Umeå : Umeå University

    Författare :Alireza Salami; Umeå universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; multivariate analysis; univariate analysis; multimodal imaging; episodic memory; aging; functional magnetic resonance imaging; diffusion tensor imaging; biology; biologi; Psychology; psykologi; datoriserad bildanalys; Computerized Image Analysis;

    Sammanfattning : Functional brain images are extraordinarily rich data sets that reveal distributed brain networks engaged in a wide variety of cognitive operations. It is a substantial challenge both to create models of cognition that mimic behavior and underlying cognitive processes and to choose a suitable analytic method to identify underlying brain networks. LÄS MER

  2. 2. Multivariate design of molecular docking experiments An investigation of protein-ligand interactions

    Detta är en avhandling från Umeå : Umeå universitet. Kemiska institutionen

    Författare :David Andersson; Umeå universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular docking; chemometrics; multivariate analysis; principal component analysis; PCA; design of experiments; DoE; partial least-square projections to latent structures; PLS; scoring functions; ligand-binding cavity; major histocompatibility complex; MHC; glycopeptide; T-cell.; NATURAL SCIENCES Chemistry Organic chemistry Pharmaceutical chemistry; NATURVETENSKAP Kemi Organisk kemi Läkemedelskemi; läkemedelskemi; läkemedelskemi;

    Sammanfattning : To be able to make informed descicions regarding the research of new drug molecules (ligands), it is crucial to have access to information regarding the chemical interaction between the drug and its biological target (protein). Computer-based methods have a given role in drug research today and, by using methods such as molecular docking, it is possible to investigate the way in which ligands and proteins interact. LÄS MER

  3. 3. Multivariate Measurements and Chemical Imaging of Organic Compounds

    Detta är en avhandling från Umeå : Umeå universitet. Kemiska institutionen

    Författare :Johan Engelbrektsson; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Image analysis; Spectroscopy; Hyperspectral; Chemical Imaging; PCA; PLS; SERS; Wavelet Transform; Multivariate analysis;

    Sammanfattning : Chemical imaging is an emerging analytical technique, based on the interplay between, most often, spectroscopic measurements and advanced evaluation methodology. With this we can study the distribution of chemical compounds in different compartments, such as individual cells and pharmaceutical tablets. LÄS MER

  4. 4. Compact-disc microfluidic methods for characterization of therapeutic antibodies Analysis of post-translational modifications

    Detta är en avhandling från Stockholm : Department of Analytical Chemistry, Stockholm University

    Författare :Thi Thuy Tran; Stockholms universitet.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microfluidic CD; therapeutic antibodies; post-translational modifications; glycosylation profiling; multivariate statistical analysis; MALDI-MS; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Characterization of post-translational modifications (PTMs) of therapeutic proteins is very important during the bioprocess development to maintain desired product quality and during the submission process to regulatory authorities for product approval. Monitoring glycosylation in pharmacokinetic studies can be useful to evaluate the dependence of clearance rates on different glycoforms. LÄS MER

  5. 5. Influences of Statistical Analyses on Result Presentations of Oral Implant Treatment

    Detta är en avhandling från Stockholm : Department of Analytical Chemistry, Stockholm University

    Författare :Irene Herrmann; Göteborgs universitet.; Gothenburg University.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Statistical methods; oral implants; dependence; prognostic risk factors; multivariate analysis; bone-combination; Jackknife; log rank test; variance;

    Sammanfattning : Abstract Evaluation of oral implants involves at least three major components: statistical methods, study design and success criteria. The aims of the current thesis were to investigate how different statistical methods affect the outcome of oral implant treatment and to statistically determine if any dependence among implants placed in the same jaw exists. LÄS MER