Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Mechanisms of Interferon-α Induction in Systemic Lupus Erythematosus

   Författare :Ullvi Båve; Lars Rönnblom; Gunnar V. Alm; Ingrid Lundberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Systemic lupus erythematosus; interferon inducer; apoptosis; autoantibodies; natural interferon-alpha producing cell; FcgammaRII; Sjögren´s syndrome; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicine; medicin;

   Sammanfattning : Patients with systemic lupus erythematosus (SLE) have an activated type I interferon (IFN) system with an ongoing IFN-α synthesis. This may be caused by circulating immune complexes, consisting of anti-DNA antibodies (Abs) and DNA, with IFN-α inducing capacity. LÄS MER

3. 2. Human adipose tissue. Genes predominantly expressed in the visceral depot and in hypertrophic adipocytes

   Författare :Jenny Palming; Göteborgs universitet; []
   Nyckelord :obesity; type 2 diabetes; adipose tissue depots; complement system; plasma cell; Fc receptor; serum amyloid A; NAD P H:quinone oxidoreductase 1; DNA microarray;

   Sammanfattning : The obesity prevalence is increasing worldwide and obesity is closely linked to type 2 diabetes and cardiovascular disease. Both visceral fat accumulation and enlarged adipocyte size are risk factors for obesity related metabolic disorders. LÄS MER