Sökning: "Fattori di trascrizione"

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1. 1. Molecular characterization of FOX factors and Wnt signalling interplay in human cancers

   Författare :Giulia Pizzolato; Stefan Koch; Åsa Keita; Boudewijn Burgering; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FOX proteins; Wnt signalling; p53; Tumour biology; Transcription factors; Proteine FOX; Via di segnalazione Wnt; p53; Biologia dei tumori; Fattori di trascrizione;

   Sammanfattning : Wnt/β-catenin signalling, also referred to as canonical Wnt signalling, is a critical regulator of tissue homeostasis and of the differentiation of cells during development. The outcome of canonical Wnt pathway activity is defined by the regulation of target gene transcription, which ultimately determines cell identity and proliferation. LÄS MER