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1. 1. Autoproteolysis accelerated by conformational strain - a novel biochemical mechanism

   Författare :Denny Johansson; Göteborgs universitet; []
   Nyckelord :SEA domain; autoproteolysis; MUC1; conformational strain; protein folding;

   Sammanfattning : Natural fragmentation of polypeptide chains by autoproteolysis occurs in a number of protein families. It is a vital step in the maturation of several enzymes and in the formation of membrane-associated mucins that constitute a part of the protective mucus barrier lining epithelial cells. LÄS MER